1. Wayne EJ: The diagnosis of thyrotoxicosis. Br Med J 1:411, 1954.
1.1.Sawin CT, Geller A, Kaplan MM, Bacharach P, Wilson PWF, Hershman JM. Low serum thyrotropin (thyroid stimulating hormone) in older persons without hyperthyroidism. Arch Intern Med 151:165-168, 1991.
2. Morley JE, Shafer RB, Elson MK, Slag MF, Raleigh MJ, Brammer GL, Yuwiler A, Hershman JM: Amphetamine-induced hyperthyroxinemia. Ann Intern Med 93:707, 1980.
3. Brown ME, Refetoff S: Transient elevation of serum thyroid hormone concentration after initiation of replacement therapy in myxedema. Ann Intern Med 92:491, 1980.
4. Kaptein EM, Macintyre SS, Weiner JM, Spencer CA, Nicoloff JT: Free thyroxine estimates in nonthyroidal illness: Comparison of eight methods. J Clin Endocrinol Metab 52:1073, 1981.
5. Engler D, Donaldson EB, Stockigt JR, Taft P: Hyperthyroidism without triiodothyronine excess: An effect of severe nonthyroidal illness. J Clin Endocrinol Metab 46:77, 1978.
6. Mayfield RK, Sagel J, Colwell JA: Thyrotoxicosis without elevated serum triiodothyronine levels during diabetic ketoacidosis. Arch Intern Med 140:408, 1980.
7. Sobrinho LG, Limbert ES, Santos MA: Thyroxine toxicosis in patients with iodine induced thyrotoxicosis. J Clin Endocrinol Metab 45:25, 1977.
8. Sterling K, Refetoff S, Selenkow HA: T3 thyrotoxicosis due to elevated serum triiodothyronine levels. J Amer Med Assn 213:571, 1970.
9. Hollander CS, Nihei N, Burday SZ, Mitsuma T, Shenkman L, Blum M: Clinical and laboratory observations in cases of triiodothyronine toxicosis confirmed by radioimmunoassay. Lancet 1:609, 1972.
10. Hollander CS, Mitsuma T, Shenkman L, Stevenson C, Pineda G, Silva E: T3 toxicosis in an iodine-deficient area. Lancet 2:1276, 1972.
10.1. Murakami M, Miyashita K, Kakizaki S, Saito S, Yamada M, Iriuchijima T, Takeuchi T, Mori M. Clinical usefulness of thyroid-stimulating antibody measurement using Chinese hamster ovary cells expressing human thyrotropin receptors. Eur J Endocrinol 1995:80-86, 1995.
10.11: Costagliola S, Morgenthaler NG, Hoermann R, Badenhoop K, Struck J, Freitag D, Poertl S, Weglohner W, Hollidt JM, Quadbeck B, Dumont JE, Schumm-Draeger PM,
Bergmann A, Mann K, Vassart G, Usadel KH. Second generation assay for thyrotropin receptor antibodies has superior diagnostic sensitivity for Graves' disease.J Clin Endocrinol Metab. 1999 Jan;84(1):90-7.
11. Hollander CS, Mitsuma T, Kastin AJ, Shenkman L, Blum M, Anderson DG: Hypertriiodothyroninemia as a premonitory manifestation of thyrotoxicosis. Lancet 2:731, 1971.
11.1. Takasu N, Oshiro C, Akamine H, Komiya I, Nagata A, Sato Y, Yoshimura H, Ito K. Thyroid-stimulating antibody and TSH-binding inhibitor immunoglobulin in 277 Graves’ patients and in 686 normal subjects. J Endocrinol Invest 20:452-461, 1997.
11.2. Feldt-Rasmussen U, Schleusener H, Carayon P. Meta-analysis evaluation of the impact of thyrotropin receptor antibodies on long-term remission after medical therapy of Graves’ disease. J Clin Endocrinol Metab 78:98-102, 1994.
12. Burrow GN. Thyroid dysfunction in the Recently pregnant: Post-partum thyroiditis. Thyroid 4:363-365,1994.
13. Ormston BJ, Alexander L, Evered DC, Clark F, Bird T, Appleton D, Hall R: Thyrotropin response to thyrotropin-releasing hormone in ophthalmic Graves' disease: Correlation with other aspects of thyroid function, thyroid suppressibility and activity of eye signs. Clin Endocrinol 2:369, 1973.
14. Franco PS, Hershman JM, Haigler ED, Pittman JA: Response to thyrotropin-releasing hormone compared with thyroid suppression tests in euthyroid Graves' disease. Metabolism 22:1357, 1973.
15. Clifton-Bligh P, Silverstein GE, Burke G: Unresponsiveness to thyrotropin-releasing hormone (TRH) in treated Graves' hyperthyroidism and in euthyroid Graves' disease. J Clin Endocrinol Metab 38:531, 1974.
16. Bolk JH, Bussemaker JK, Elte JWF, Haak A, van der Heide D: Thyroid stimulating immunoglobulins do not cause non- autonomous, autonomous, or toxic multinodular goiters. Lancet 2:61, 1979.
16.1 Watson SG, Radford AD, Kipar A, Ibarrola P, Blackwood L Somatic mutations of the thyroid-stimulating hormone receptor gene in feline hyperthyroidism: parallels with human hyperthyroidism.J Endocrinol. 2005 Sep;186(3):523-37.
17. Namba H, Ross JL, Goodman D, Fagin JA: Solitary polyclonal autonomous thyroid nodule: A rare cause of childhood hyperthyroidism. J Clin Endocrinol Metab 72:1108-1112, 1991.
18. Shimaoka K, Van Herle AJ, Dindogru A: Thyrotoxicosis secondary to involvement of the thyroid with malignant lymphoma. J Clin Endocrinol Metab 43:64, 1976.
19. Spanheimer RG, Bar RS, Hayford JC: Hyperthyroidism caused by inappropriate thyrotropin hypersecretion. Studies in patients with selective pituitary resistance to thyroid hormone. Arch Intern Med 142:1283-1286, 1982.
20. Emerson CH, Utiger RD: Hyperthyroidism and excessive thyrotropin secretion. N Engl J Med 287:328, 1972.
21. Gershengorn ML: Thytropin-induced hyperthyroidism caused by selective pituitary resistance to thyroid hormone. A new syndrome of "inappropriate secretion of TSH". J Clin Invest 56:271, 1975.
22. Woolf PD, Daly R: Thyrotoxicosis with painless thyroiditis. Am J Med 60:73, 1976.
23. Gluck FB, Nusynowitz ML, Plymate S: Chronic lymphocytic thyroiditis, thyrotoxicosis, and low radioactive iodine uptake. N Engl J Med 293:624, 1975.
24. Ginsberg J, Walfish PG: Post-partum transient thyrotoxicosis with painless thyroiditis. Lancet 1:1125, 1977.
25. Amino N, Yabu Y, Miyai K, Fujie T, Azukizawa M, Onishi T, Kumahara Y: Differentiation of thyrotoxicosis induced by thyroid destruction from Graves' disease. Lancet 1:344, 1978.
26. Inada M, Nishikawa M, Naito K, Ishii H, Tanaka K, Imura H: Reversible changes of the histological abnormalities of the thyroid in patients with painless thyroiditis. J Clin Endocrinol Metab 52:431, 1981.
27. Yabu Y, Amino N, Mori H, Miyai K, Tanizawa O, Takai S-I, Kumahara Y, Matsusuka F, Kuma K: Postpartum recurrence of hyperthyroidism and changes of thyroid-stimulating immunoglobulins in Graves' disease. J Clin Endocrinol Metab 51:1454, 1980.
28. Amino N, Miyai K, Azukizawa M, Yabu Y, Fujie T, Onishi T, Kumahara Y: Differentiation of thyrotoxicosis induced by thyroid destruction from Graves' disease. Lancet 2:344, 1978.
29. Shigemasa C, Ueta Y, Mitani Y, Taniguchi S, Urabe K, Tanaka T, Yoshida A, Mashiba H: Chronic thyroiditis with painful tender thyroid enlargement and transient thyrotoxicosis. J Clin Endocrinol Metab 70:385, 1990.29.2. Rodien P. Bremont C. Sanson ML. Parma J. Van Sande J. Costagliola S. Luton JP. Vassart G. Duprez L. Familial gestational hyperthyroidism caused by a mutant thyrotropin receptor hypersensitive to human chorionic gonadotropin. New England Journal of Medicine. 339(25):1823-6, 1998 .
29.1. Fuhrer D, Wonerow P, Willgerodt H, Paschke R. Identification of a new thyrotropin receptor germline mutation (Leu629 Phe) in a family with neonatal onset of autosomal dominant nonautoimmune hyperthyroidism. J Clin Endocrinol Metab 82:4234-4238, 1997.
29.1. Sarlis NJ, Brucker-Davis F, Swift JP, Tahara K, Kohn LD. Graves’ disease following thyrotoxic painless thyroiditis. Analysis of antibody activities against the thyrotropin receptor in two cases. Thyroid 7:829, 1997.
29.3. Ginsberg J, Lewanczuk RZ, Honore LH. Hyperplacentosis: a novel cause of hyperthyroidism. Thyroid 11:393-396, 2001.
29.3. Goodwin TM, Hershman JM. Hyperthyroidism due to inappropriate production of human chorionic gonadotropin. Clin Obstet Gynecol 40:32-44, 1997.
29.4. Yoshimura M, Hershman JM. Thyrotropic action of human chorionic gonadotropin. Thyroid 5:425-434, 1995.
29.5 Hershman JM. 1999 Human chorionic gonadotropin and the thyroid: hyperemesis gravidarum and trophoblastic tumors. Thyroid 9:653.
30. Cave WT Jr, Dunn JT: Choriocarcinoma with hyperthyroidism: Probable identity of the thyrotropin with human chorionic gonadotropin. Ann Intern Med 85:60, 1976.
31. Nagataki S, Mizuno M, Sakamoto S, Irie M, Shizume K, Nakao K, Galton VA, Arky RA, Ingbar SH: Thyroid function in molar pregnancy. J Clin Endocrinol Metab 44:254, 1977.
32. Tsuruta E, Tada H, Tamaki H, Kashiwai T, Asahi K, Takeoka K, Mitsuda N, Amino N. Pathogenic role of asialo human chorionic gonadotropin in gestational thyrotoxicosis. J Clin Endocrinol Metab 80:350-355, 1995.
33. Miyai K, Tanizawa O, Yamamoto T, Azukizawa M, Kawai Y, Noguchi M, Ishibas K, Kumahara Y: Pituitary-thyroid function in trophoblastic disease. J Clin Endocrinol Metab 42:254, 1976.
33.1 Doi F, Kakizaki S, Takagi H, Murakami M, Sohara N, Otsuka T, Abe T, Mori M .Long-term outcome of interferon-alpha-induced autoimmune thyroid disorders in chronic hepatitis C.Liver Int. 2005 Apr;25(2):242-6
33.2 Chen F, Day SL, Metcalfe RA, Sethi G, Kapembwa MS, Brook MG, Churchill D, de Ruiter A, Robinson S, Lacey CJ, Weetman AP.Characteristics of autoimmune thyroid disease occurring as a late complication of immune reconstitution in patients with advanced human immunodeficiency virus (HIV) disease.Medicine (Baltimore). 2005 Mar;84(2):98-106.
33a. Sgarbi, JA; Villaca, FG; Garbeline, B; Villar, HE; Romaldini, JH. The effects of early antithyroid therapy for endogenous subclinical hyperthyroidism in clinical and heart abnormalities. J Clin Endocrinol Metab 88 1672-1677 2003
33b Woeber KA.Observations concerning the natural history of subclinical hyperthyroidism.Thyroid. 2005 Jul;15(7):687-91
34. Lahey FH: Apathetic thyroidism. Ann Surg 93:1026, 1931.
35. Editorial: Apathetic thyrotoxicosis. Lancet 2:809, 1970.
36. Philip JR, Harrison MT, Ridley EF, Crooks J: Treatment of thyrotoxicosis with ionizing radiation. Lancet 2:1307, 1968.
36.1. Franklyn, JA. The management of hyperthyroidism. New Engl J Med 330:1731-1738, 1994.
36.2. Torring O, Tallstedt L, Wallin G, Lundell G, Lunggren J-G, Taube A, Saaf M, Hamberger B, Thyroid Study Group. Graves’ hyperthyroidism: treatment with antithyroid drugs, surgery, or radioiodine – A prospective, randomized study. J Clin Endocrinol Metab 81:2986-2993, 1996.
36.3. Vitti P, Rago T, Chiovato L, Pallini S, Santini F, Fiore E, Rocchi R, Martino E, Pinchera A. Clinical features of patients with Graves’ disease undergoing remission after antithyroid drug treatment. Thyroid 7:369, 1997.
36.4 Scholz, GH; Hagemann, E; Arkenau, C; Engelmann, L; Lamesch, P; Schreiter, D; Schoenfelder, M; Olthoff, D; Paschke, R. Is there a place for thyroidectomy in older patients with thyrotoxic storm and cardiorespiratory failure? Thyroid 13 933 2003
37. Glinoer D, Hesch D, LaGasse R, Laurberg P: The management of hyperthyroidism due to Graves' disease in Europe in 1986. Results of an international survey. Proceedings of the Symposium held during the 15th Annual Meeting of the European Thyroid Association in Stockholm, June - July, 1986, 37 pages.
38. Solomon B, Glinoer D, LaGasse R, Wartofsky L: Current trends in the management of Graves' disease. J Clin Endocrinol Metab 70:1518-1524, 1990.
39. Dobyns BM, Sheline GE, Workman JB, Tompkins EA, McConahey WM, Becker DV: Malignant and benign neoplasms of the thyroid in patients treated for hyperthyroidism: a report of the Cooperative Thyrotoxicosis Therapy Follow-up Study. J Clin Endocrinol Metabl 37:976-998, 1974.
40. Safa AM, Schumacher P, Rodriguez-Antunez A: Long-term follow-up results in children and adolescents treated with radioactive iodine (131-Iodine). N Engl J Med 292:167-171, 1975.
41. Holm LE, Dahlqvist I, Israelsson A, Lundell GM: Malignant thyroid tumors after 131-iodine therapy. N Engl J Med 303:188-191, 1980.
42. Hamburger JI: Management of hyperthyroidism in children and adolescents. J Clin Endocrinol Metab 60:1019, 1985.
43. Freitas JE, Swanson DP, Gross MD, Sisson JS: Iodine-131: Optimal therapy for hyperthyroidism in children and adolescents? J Nucl Med 20:847, 1979.
44. Hayek A, Chapman E, Crawford JD: Long-term results of treatment of thyrotoxicosis in children and adolescents with radioactive iodine. N Engl J Med 283:949, 1970.
44.1.Franklyn JA, Maisonneuve P, Sheppard M, Betteridge PB. Cancer indicdence and mortality after radioiodine treatment for hyperthyroidism: a population based cohort study. Lancet 353:2111-15, 1999
44.2 Rivkees SA, Dinauer C. An optimal treatment for pediatric Graves' disease is radioiodine.J Clin Endocrinol Metab. 2007 Mar;92(3):797-800.
45. Chapman EM: History of the discovery and early use of radioactive iodine. J Amer Med Assn 250:2042-2044, 1983.
46. Chapman EM, Maloof F: The use of radioactive iodine in the diagnosis and treatment of hyperthyroidism: Ten years' experience. Medicine 34:261, 1955.
47. Blahd W, Hays MT: Graves' disease in the male. A review of 241 cases treated with an individually calculated dose of sodium iodide 131I. Arch Intern Med 129:33, 1972.
47.1 Bajnok L, Mezosi E, Nagy E, Szabo J, Sztojka I, Varga J, et al. 1999 Calculation of the radioiodine dose for the treatment of Graves' hyperthyroidism: Is more than seven-thousand rad target dose necessary? Thyroid 9:865.
47.2 Leslie, WD; Ward, L; Salamon, EA; Ludwig, S; Rowe, RC; Cowden, EA. A randomized comparison of radioiodine doses in Graves’ hyperthyroidism. J Clin Endocrinol Metab 88 978-983 2003
48. Hagen F, Ouelette RP, Chapman EM: Comparison of high and low dosage levels of 131I in the treatment of thyrotoxicosis. N Engl J Med 277:559, 1967.
49. Cevallos JL, Hagen GA, Maloof F, Chapman EM: Low-dosage 131I therapy of thyrotoxicosis (diffuse goiters). N Engl J Med 290:141, 1974.
50. Ross DS, Daniels GH, De Stafano P, Maloof F, Ridgway EC: Use of adjunctive potassium iodide after radioactive iodine (131I) treatment of Graves' hyperthyroidism. J Clin Endocrinol Metab 57:250, 1983.
51. Reinwein D, Schaps D, Berger H, Hackenberg K, Horster FA, Klein E, Von Zur Muhlen A, Wendt RU, Wildmeister W: Hypothyreoserisyiko nach fraktionierter Radiojodtherapie. Dtsch Med Wochenschr 98:1789, 1973.
52. Rapoport B, Caplan R, DeGroot L: Low-dose sodium iodide 131I therapy in Graves' disease. J Amer Med Assn 224:1610, 1973.
53. Roudebush CP, Hoye KE, DeGroot LJ: Compensated low-dose 131I therapy of Graves' disease. Ann Intern Med 87:441, 1977.
54. Sridama V, McCormick M, Kaplan EL, Fauchet R, DeGroot LJ: Long-term follow-up study of compensated low-dose 131I therapy for Graves' disease. N Engl J Med 311:426-432, 1984.
55. Glennon JA, Gordon ES, Sawin CT: Hypothyroidism after low- dose I131 treatment of hyperthyroidism. Ann Intern Med 76:721, 1972.
56. Saito S, Sakurada T, Yamamoto M, Yoshida K, Kaise K, Kaise N, Yoshinaga K: Long term results of radioiodine 131I therapy in 331 patients with Graves' disease. Tokyo J Exp Med 132:1-10, 1980.
57. DeGroot LJ, Mangklabruks A, McCormick M: Comparison of RA 131I treatment protocols for Graves' disease. J Endocrinol Invest 13:111-118, 1990.
57.1. Berg G, Michanek A, Holmberg E, Nystrom E. Clinical outcome of radioiodine treatment of hyperthyroidism: a follow-up study. J Intern Med 239:165-171, 1996.
57.2. Rini JN, Vallabhajosula S, Zanzonico P, Hurley JR, Becker DV, Goldsmith SJ. Thyroid uptake of liquid versus capsule 131-I tracers in hyperthyroid patients treated with liquid 131-I. Thyroid 9:347, 1999
58. Wise PH, Burnet RB, Ahmad A, Harding PE: Intentional radioiodine ablation in Graves' disease. Lancet 2:1231, 1975.
58.2. Allahabadia A, Daykin J, Sheppard MC, Gough SCL, Franklyn JA. Radioiodine treatment of hyperthyroidism—prognostic factors for outcome. J Clin Endocrinol Metab 86:3611-3617, 2001.
58.3: Leslie WD, Ward L, Salamon EA, Ludwig S, Rowe RC, Cowden EA. A randomized comparison of radioiodine doses in Graves' hyperthyroidism.J Clin Endocrinol Metab. 2003 Mar;88(3):978-83.
58.31 Bonnema SJ, Bennedbaek FN, Veje A, Marving J, Hegedus L.Continuous methimazole therapy and its effect on the cure rate of hyperthyroidism using radioactive iodine: an evaluation by a randomized trial. J Clin Endocrinol Metab. 2006 Aug;91(8):2946-51.
59. Marcocci C, Gianchecchi D, Masini I, Golia F, Ceccarelli C, Bracci E, Fenzi GF, Pinchera A: A reappraisal of the role of methimazole and other factors on the efficacy and outcome of radioiodine therapy of Graves' hyperthyroidism. J Endocrinol Invest 13:513-520, 1990.
59.1. Glinoer D, Verelst J. Use of 131-Iodine for the treatment of hyperthyroidism in adults. Annales d Endocrinologie 57:177-185, 1996.
59.2 Nakazato N, Yoshida K, Mori K, Kiso Y, Sayama N, Tani J-I, et al. 1999 Antithyroid drugs inhibit radioiodine-induced increases in thyroid autoantibodies in hyperthyroid Graves' disease. Thyroid 9:775.
59.2. Andrade VA, Gross JL, Maia AL. The effect of methimazole pretreatment on the efficacy of radioactive iodine therapy in Graves’ hyperthyroidism: one-year follow-up of a prospective, randomized study. J Clin Endocrinol Metab 86:3488-3493, 2001.
59.3. Burch HB, Solomon BL, Cooper DS, Ferguson P, Walpert N, Howard R. The effect of antithyroid drug pretreatment on acute changes in thyroid hormone levels after 131I ablation for Graves’ disease. J Clin Endocrinol Metab 86:3016-3021, 2001.
59.4: Bonnema SJ, Bennedbaek FN, Veje A, Marving J, Hegedus L. Propylthiouracil before 131I therapy of yperthyroid diseases: effect on cure rate evaluated by a randomized clinical trial.J Clin Endocrinol Metab. 2004 Sep;89(9):4439-44.
60. Greig WR, Gillespie FC, Thomson JA, McGirr EM: Iodine-125 treatment for thyrotoxicosis. Lancet 1:755, 1969.
61. Editorial: Radioiodine treatment of thyrotoxicosis. Lancet 1:23,1972.
62. Bremmer WF, Greig WR, McDougall IR: Results of treating 297 thyrotoxic patients with 125I. Lancet 2:281, 1973.
63. Benua RS, Dobyns BM: Isolated compounds in the serum, disappearance of radioactive iodine from the thyroid, and clinical response in patients treated with radioactive iodine. J Clin Endocrinol Metab 15:118, 1955.
63.1. Stensvold AD, Jorde R, Sundsfjord J. Late and transient increases in free T4 after radioiodine treatment for Graves’ disease. J Endocrinol Invest 20:580-584, 1997.
64. Stanbury JB, Janssen MA: The iodinated albumin-like component of the plasma of thyrotoxic patients. J Clin Endocrinol Metab 22:978, 1962.
64a. Dale J, Daykin J, Holder R, Sheppard MC, Franklyn JA. Weight gain following treatment of hyperthyroidism. Clin Endocrinol 55:233-239, 2001.
65. Goldsmith RE: Radioisotope therapy for Graves' disease. Mayo Clin Proc 47:953, 1972.
66. Slingerland WD, Hershman JM, Dell E, Burrows B: Thyrotropin and PBI in radioiodine-treated hyperthyroid patients. J Clin Endocrinol Metab 35:912, 1972.
67. Gordin A, Wagar G, Hernberg CA: Serum thyrotropin and response to thyrotrophin-releasing hormone in patients who are euthyroid after radioiodine treatment for hyperthyroidism. Acta Med Scand 194:335, 1973.
68. Baldwin WW: Graves' disease succeeded by atrophy. Lancet 1:145,1895.
69. Wood LC, Ingbar SH: Hypothyroidism as a late sequela in patients with Graves' disease treated with antithyroid drugs. J Clin Invest 64:1429, 1979.
69a. Tigas S, Idiculla J, Beckett G, Toft A. Is excessive weight gain after ablative treatment of hyperthyroidism due to inadequate thyroid hormone therapy? Thyroid 10:1107, 2000.
70. Creutzig H, Kallfelz I, Haindl J, Thiede G, Hundeshagen H: Thyroid storm and iodine-131 treatment. Lancet 2:145, 1976.
71. Creutzig H, Kallfelz I, Haindl J, Thiede G, Hundeshagen H: Thyroid storm and iodine-131 treatment. Lancet 2:145, 1976.
72. Lamberg BA, Hernberg CA, Wahlberg P, Hakkila R: Treatment of toxic nodular goiter with radioactive iodine. Acta Med Scand 165:245, 1959.
73. McDermott MT, Kidd GS, Dodson Jr LE, Hofeldt FD: Radioiodine-induced thyroid storm. Case report and literature review. Amer J Med 75:353, 1983.
74. Townsend JD: Hypoparathyroidism following radioactive iodine therapy for intractable angina pectoris. Ann Intern Med 55:662, 1961.
75. Gilbert-Dreyfus MZ, Gali P: Cataract due to tetany following radioactive iodine therapy. Sem Hop Paris 34:1301, 1958.
76. Fulop M: Hypoparathyroidism after 131I therapy. Ann Intern Med 75:808, 1971.
76.1 Ceccarelli C, Canale D, Battisti P, Caglieresi C, Moschini C, Fiore E, Grasso L, Pinchera A, Vitti P.Testicular function after 131I therapy for hyperthyroidism.Clin Endocrinol (Oxf). 2006 Oct;65(4):446-52.
76a. Franklyn JA, Sheppard MC, Maisonneuve P. Thyroid function and mortality in patients treated for hyperthyroidism. JAMA. 2005 Jul 6;294(1):71-80.
77. Fenzi G, Hashizume K, Roudebush C, DeGroot LJ: Changes in thyroid stimulating immunoglobulins during antithyroid therapy. J Clin Endocrinol Metab 48:572, 1979.
78. Teng CS, Yeung RTT, Khoo RKK, Alagaratnam TT: A prospective study of the changes in thyrotropin binding inhibitory immunoglobulins in Graves' disease treated by subtotal thyroidectomy or radioactive iodine. J Clin Endocrinol Metab 50:1005, 1980.
79. Sridama V, DeGroot LJ: Treatment of Graves' disease and the course of ophthalmopathy. Amer J Med 87:70-73, 1989.
80. Tallstedt L, Lundell G, Torring O, Wallin G, Ljunggren J-G, Blomgren H, Taube A. Occurrence of ophthalmopathy after treatment for Graves' disease. N Engl J Med 326:1733-1738, 1992.
80.1. Fernandez Sanchez JR, Rosell Pradas J, Carazo Martinez O, Torres Vela E, Escobar Jimenez F, Garbin Fuentes I, Vara Thorbeck R. Graves’ ophthalmopathy after subtotal thyroidectomy and radioiodine therapy. Brit J Surg 80:1134-1136, 1993.
81. Gamstedt A, Wadman B, Karlsson A: Methimazole, but not betamethasone, prevents 131I treatment-induced rises in thyrotropin receptor autoantibodies in hyperthyroid Graves' disease. J Clin Endocrinol Metab 62:773-777, 1986.
82. Bartalena L, Marcocci C, Bogazzi F, Panicucci M, Lepri A, Pinchera A: Use of corticosteroids to prevent progression of Graves' ophthalmopathy after radioiodine therapy for hyperthyroidism. N Engl J Med 321:1349-1352, 1989.
82.1. Bartalena L, Marcocci C, Bogazzi F, Manetti L, Tanda ML, Dell’Unto E, Bruno-Bossio G, Nardi M, Bartolomei MP, Lepri A, Rossi G, Martino E, Pinchera A. Relation between therapy for hyperthyroidism and the course of Graves’ ophthalmopathy. N Engl J Med 338:73-78, 1998.
82.2 Takamura Y, Nakano K, Uruno T, Ito Y, Miya A, Kobayashi K, Yokozawa T,Matsuzuka F, Kuma K, Miyauchi A. Changes in serum TSH receptor antibody (TRAb) values in patients with Graves' disease after total or subtotal thyroidectomy. Endocr J. 2003 Oct;50(5):595-601.
82.3 Jensen BE, Bonnema SJ, Hegedus L.Glucocorticoids do not influence the effect of radioiodine therapy in Graves' disease.Eur J Endocrinol. 2005 Jul;153(1):15-21.
83. DeGroot LJ, Paloyan E: Thyroid carcinoma and radiation. A Chicago endemic. J Amer Med Assn 225:487, 1973.
84. Clark DW: Association of irradiation with cancer of the thyroid in children and adolescents. J Amer Med Assn 159:1007, 1955.
85. Simpson CL, Hempelmann LH, Fuller LM: Neoplasia in children treated with x-rays in infancy for thymic enlargement. Radiology 64:840, 1955.
86. Doniach I: The effect of radioactive iodine alone and in combination with methylthiouracil upon tumor production in the rat's thyroid gland. Br J Cancer 7:181, 1953.
87. Sampson RJ, Key CR, Buncher CR, Iijuma S: Thyroid carcinoma in Hiroshima and Nagasaki. J Amer Med Assn 209:65, 1969.
88. Conard RA, Dobyns BM, Sutow W: Thyroid neoplasia as late effect of exposure to radioactive iodine in fallout. J Amer Med Assn 214:316, 1970.
89. Saenger EL, Seltzer RA, Sterling TD, Kereiakes JG: Carcinogenic effects of 131I compared with x-irradiation -- A review. Health Phys 9:1371, 1963.
89.1.Pacini F, Vorontsova T, Demidchik E, Molinaro E, Agate L, Romei C, Shavrova E, Cherstvoy E, Ivashkevitch Y, Kuchinskaya E, Schlumberger M, Rouga G, Felesi M, Pinchera A. Post-Chernobyl thyroid carcinoma in Belarus children and adolescents: comparison with naturally occurring thyroid carcinoma in Italy and France. J Clin Endocrinol Metab 82:3563-3569, 1997.
90. Pochin EE: Leukemia following radioiodine treatment of thyrotoxicosis. Br Med J 2:1545, 1960.
91. Saenger EL, Thoma GE, Tompkins EA: Incidence of leukemia following treatment of hyperthyroidism. J Amer Med Assn 205:855, 1968.
92. Biological effects of ionizing radiation V. The health effects of exposure to low levels of ionizing radiation, report of the Advisory Committee on the Biological Effects of Ionizing Radiation, National Research Council, Washington, DC, Natl Acad Press, 1990.
93. Russell WL, Kelly EM: Mutation frequencies in male mice and the estimation of genetic hazards of radiation in men. Proc Natl Acad Sci USA 79:542, 1982.
94. Webster EW, Merrill OE: Radiation hazards: II. Measurements of gonadal dose in radiographic examination. N Engl J Med 257:811, 1957.
95. Robertson J, Gorman CA: Gonadal radiation dose and its genetic significance in radioiodine therapy of hyperthyroidism. J Nucl Med 17:826, 1976.
96. Sarkar SD, Bierwaltes WH, Gill SP, Cowley BJ: Subsequent fertility and birth histories of children and adolescents treated with 131I for thyroid cancer. J Nucl Med 17:460, 1976.
97. Hollingsworth JW: Delayed radiation effects in survivors of the atomic bombings: A summary of the findings fo the Atomic Bomb Casualty Commission, 1947-1959. N Engl J Med 263:481, 1960.
97.1 Dardano A, Ballardin M, Ferdeghini M, Lazzeri E, Traino C, Caraccio N, Mariani G, Barale R, Monzani F.Anticlastogenic effect of Ginkgo biloba extract in Graves' disease patients receiving radioiodine therapy.J Clin Endocrinol Metab. 2007 Nov;92(11):4286-9.
98. Plummer HS: Results of administering iodine to patients having exophthalmic goiter. J Amer Med Assn 80:1955, 1923.
99. MacKenzie CG, MacKenzie JB: Effect of sulfonamides and thiourea on the thyroid gland and basal metabolism. Endocrinology 32:185, 1943.
100. Astwood EB: Treatment of hyperthyroidism with thiourea and thiouracil. J Amer Med Assn 122:78, 1943.
101. Marcocci C, Chiovato L, Mariotti S, Pinchera A: Changes of circula-ting thyroid autoantibody levels during and after therapy with methi-mazole in patients with Graves' disease. J Endocrinol Invest 5:13, 1982.
102. Pinchera A, Liberti P, Martino E, Fenzi GF, Grasso L, Rovis I, Baschieri L: Effects of antithyroid therapy on the long-acting thyroid stimulator and the antithyroglobulin antibodies. J Clin Endocrinol Metab 29:231, 1969.
103. MacGregor AM, Ibbertson HK, Smith BR, Hall R: Carbimazole and autoantibody synthesis in Hashimoto's thyroiditis. Br Med J 281:968, 1980.
104. McGregor AM, Petersen MM, McLachlan SM, Rooke P, Smith BR, Hall R: Carbimazole and the autoimmune response in Graves' disease. N Engl J Med 303:302, 1980.
105. Hallengren B, Forsgren A, Melander A: Effects of antithyroid drugs on lymphocyte function in vitro. J Clin Endocrinol Metab 51:298, 1980.
105.1. Weetman AP. The immunomodulatory effects of antithyroid drugs. Thyroid 4:145-146, 1994.
106. Ludgate ME, McGregor AM, Weetman AP, Ratanachaiyavong S, Lazarus JH, Hall R, Middleton GW: Analysis of T cell subsets in Graves' disease: alterations associated with carbimazole. Br Med J 288:526, 1984.
107. Totterman TH, Karlsson FA, Bengtsson M, Mendel-Hartvig IB: Induction of circulating activated suppressor-like T cells by methimazole therapy for Graves' disease. N Engl J Med 316:15, 1987.
108. Sridama V, Pacini F, DeGroot LJ: Decreased suppressor T- lymphocytes in autoimmune thyroid diseases detected by monoclonal antibodies. J Clin Endocrinol Metab 54:316, 1982.
109. Volpe R. Evidence that the immunosuppressive effects of antithyroid drugs are mediated through actions on the thyroid cell, modulating thyrocyte-immunocyte signaling: A review. Thyroid 4:217-223, 1994.
110.Laurberg P, Hansen PEB, Iversen E, Jensen SE, Weeke J: Goiter size and outcome of medical treatment of Graves' disease. Acta Endocrinol 111:39-43, 1986.
111. Shizume K, Irie M, Nagataki S, Matsuzaki F, Shishiba Y, Suematsu H, Tsushima T: Long-term result of antithyroid drug therapy for Graves' disease: Follow-up after more than 5 years. Endocrinol Jpn 17:327, 1970.
112. Shizume K: Long term antithyroid drug therapy for intractable cases of Graves' disease. Endocrinol Jpn 25:377, 1978.
113. Wartofsky L: Low remission after therapy for Graves' disease. Possible relation of dietary iodine with antithyroid therapy results. J Amer Med Assn 226:1083, 1973.
114. Hedley AJ, Young RE, Jones SJ, Alexander WD, Bewsher PD: Antithyroid drugs in the treatment of hyperthyroidism of Graves' disease: Long-term follow-up of 434 patients. Clin Endocrinol 31:209-218, 1989.
115. Alexander WD, McG Harden R, Koutras DA, Wayne E: Influence of iodine intake after treatment with antithyroid drugs. Lancet 2:866, 1965.
116. McMurray JF Jr, Gilliland PF, Ratliff CR, Bourland PD: Pharmacodynamics of propylthiouracil in normal and hyperthyroid subjects after a single oral dose. J Clin Endocrinol Metab 41:362, 1975.
117. Cooper DS: Which antithyroid drug? Amer J Med 80:1165- 1168, 1986.
118. Cooper DS, Goldminz D, Levin AA, Ladenson PW, Daniels GH, Molitch ME, Ridgway EC: Agranulocytosis associated with antithyroid drugs. Ann Int Med 98:26-29, 1983.
119. Barnes V, Bledsoe T: A simple test for selecting the thioamide schedule in thyrotoxicosis. J Clin Endocrinol Metab 35:250, 1972.
120. Cooper DS, Saxe VC, Meskell M, Maloof F, Ridgway EC: Acute effects of propylthiouracil (PTU) on thyroidal iodide organification and peripheral iodothyronine deiodination: Correlation with serum PTU levels measured by radioimmunoassay. J Clin Endocrinol Metab 54:101, 1982.
121. Nabil N, Miner DJ, Amatruda JM: Methimazole: An alternative route of administration. J Clin Endocrinol Metab 54:180, 1982.
121a. Zweig SB, Schlosser JR, Thomas SA, Levy CJ, Fleckman AM .Rectal administration of propylthiouracil in suppository form in patients with thyrotoxicosis and critical illness: case report and review of literature. Endocr Pract. 2006 Jan-Feb;12(1):43-47.
121.1Jongjaroenprasert W, Akarawut W, Chantasart D, Chailurkit L, Rajatanavin R. Rectal administration of propylthiouracil in hyperthyroid patients: comparison of suspension enema and suppository form. Thyroid 12:627-631, 2002
122. Greer MA, Meihoff WC, Studer H: Treatment of hyperthyroidism with a single daily dose of propylthiouracil. N Engl J Med 272:887, 1965.
123. Greer MA, Kammer H, Bouma DJ: Short-term antithyroid drug therapy for the thyrotoxicosis of Graves' disease. N Engl J Med 297:173, 1977.
124. Allannic H, Fauchet R, Orgiazzi J, Madec AM, Genetet B, Lorcy Y, Le Guerrier AM, Delambre C, Derennes V: Antithyroid drugs and Graves' disease: A prospective randomized evaluation of the efficacy of treatment duration. J Clin Endocrinol Metab 70:675, 1990.
125. Romaldini JH, Bromberg N, Werner RS, Tanaka LM, Rodrigues HF, Werner MC, Farah CS, Reiss LCF: Comparison of high and low dosage regimens of antithyroid drugs. J Clin Endocrinol Metab 57:563, 1983.
125.1. Jodar E, Munoz-Torres M, Escobar-Jimenez F, Quesada M, Luna JD, Olea N. Antiresorptive therapy in hyperthyroid patients: Longitudinal changes in bone and mineral metabolism. J Clin Endocrinol Metab 82:1989-1994, 1997.
126. Yamamoto M, Totsuka Y, Kojima I, Yamashita N, Togawa K, Sawaki N, Ogata E: Outcome of patients with Graves' disease after long-term medical treatment guided by triiodothyronine (T3) suppression test. Clin Endocrinol 19:467-476, 1983.
126.1 Azizi F, Ataie L, Hedayati M, Mehrabi Y, Sheikholeslami F.Effect of long-term continuous methimazole treatment of hyperthyroidism: comparison with radioiodine.Eur J Endocrinol. 2005 May;152(5):695-701
127. Solomon DH, Beck JC, Vanderlaan WP, Astwood EB: Prognosis of hyper-thyroidism treated by antithyroid drugs. J Amer Med Assn 152:201, 1953.
128. McLarty DG, Alexander WD, McHarden R, Robertson JWK: Self-limiting episodes of recurrent thyrotoxicosis. Lancet 1:6, 1971.
129. Thalassinos NC, Fraser TR: Effect of potassium iodide on relapse rate of thyrotoxicosis treated with antithyroid drugs. Lancet 2:183, 1971.
130. Hashizume K, Ichikawa K, Sakurai A, Suzuki S, Takeda T, Kobayashi M, Miyamoto T, Arai M, Nagasawa T: Administration of thyroxine in treated Graves' disease. Effects on the level of antibodies to thyroid-stimulating hormone receptors and on the risk of recurrence of hyperthyroidism. N Engl J Med 324:947-953, 1991.
131. Hashizume K, Ichikawa K, Nishii Y, Kobayashi M, Sakurai A, Miyamoto T, Suzuki S, Takeda T. Effect of administration of thyroxine on the risk of postpartum recurrence of hyperthyroid Graves' disease. J Clin Endocrinol Metab 75:6-10, 1992.
131.1. Rittmaster RS, Zwicker H, Abbott EC, Douglas R, Givner ML, Gupta MK, Lehmann L, Reddy S, Salisbury SR, Shlossberg AH, Tan MH, York SE. Effect of methimazole with or without exogenous L-thyroxine on serum concentrations of thyrotropin receptor antibodies in patients with Graves’ disease. J Clin Endocrinol Metab 81:3283-3288, 1996.
131.2. Lucas A, Salinas I, Rius F, Pizarro E, Granada ML, Foz M, Sanmarti A. Medical therapy of Graves’ disease: does thyroxine prevent recurrence of hyperthyroidism? J Clin Endocrinol Metab 82:2410-2413, 1997.
132. Zakarija M, McKenzie JM, Banovac K: Clinical significance of assay of thyroid-stimulating antibody in Graves' disease. Ann Intern Med 93:28, 1980.
133. Werner RS, Romaldini JH, Farah CS, Werner MC, Bromberg N. Serum thyroid-stimulating antibody, thyroglobulin levels, and thyroid suppressibility measurement as predictors of the outcome of combined methimazole and triiodothyronine therapy in Graves' disease. Thyroid 1:293, 1991.
134. Schleusener H, Schwander J, Fischer C, Holle R, Holl G, Badenhoop K, Hensen J, Finke R, Bogner U, Mayr WR, Schernthaner G, Schatz H, Pickardt CR, Kotulla P: Prospective multicenter study on the prediction of relapse after antithyroid drug treatment in patients with Graves' disease. Acta Endocrinologica (Copenh) 120:689-701, 1989.
135. Farid NR (ed): HLA in Endocrine and Metabolic Disorders. New York, Academic Press, 1981, p 357.
136. Allannic H, Fauchet R, Lorcy Y, Gueguen M, Le Guerrier A- M, Genetet B: A prospective study of the relationship between relapse of hyperthyroid Graves' disease after antithyroid drugs and HLA haplotype. J Clin Endocrinol Metab 57:719, 1983.
136.1. Michelangeli V, Poon C, Taft J, Newnham H, Topliss D, Colman P. The prognostic value of thyrotropin receptor antibody measurement in the early stages of treatment of Graves’ disease with antithyroid drugs. Thyroid 8:119, 1998.
137. Irvine WJ, Gray RS, Toft AD, Lidgard FP, Seth J, Cameron EHD: Spectrum of thyroid function in patients remaining in remission after antithyroid drug therapy for thyrotoxicosis. Lancet 1:179, 1977.
138. Buerklin EM, Schimmel M, Utiger RD: Pituitary-thyroid regulation in euthyroid patients with Graves' disease previously treated with antithyroid drugs. J Clin Endocrinol Metab 43:419, 1976.
139. Lamberg BA, Salmi J, Wagar G, Makinen T: Spontaneous hypothyroidism after antithyroid treatment of hyperthyroid Graves' disease. J Endocrinol Invest 4:399, 1981.
140. Hirota Y, Tamai H, Hayashi Y, Matsubayashi S, Matsuzuka F, Kuma K, Kumagai LF, Nagataki S: Thyroid function and histology in forty-five patients with hyperthyroid Graves' disease in clinical remission more than ten years after thionamide drug treatment. J Clin Endocrinol Metab 62:165, 1986.
141. Kampmann JP, Johansen K, Hansen JM, Helwig J: Propylthiouracil in human milk: Revision of a dogma. Lancet 1:736, 1980.
141a. Azizi F, Khoshniat M, Bahrainian M, Hedayati M. Thyroid function and intellectual development of infants nursed by mothers taking methimazole. J Clin Endocrinol Metab 85:3233-3238, 2000.
142. Wiberg JJ, Nuttall FQ: Methimazole toxicity from high doses. Ann Intern Med 77:414, 1972.
143. Chevalley J, McGavack TH, Kenigsberg S, Pearson S: A four- year study of the treatment of hyperthyroidism with methimazole. J Clin Endocrinol Metab 14:948, 1954.
144. Tajiri J, Noguchi S, Murakami T, Murakami N. Antithyroid drug-induced agranulocytosis. The usefulness of routine white blood cell count monitoring. Arch Intern Med 150:621-624, 1990.
145. Tamai H, Takaichi Y, Morita T, Komaki G, Matsubayashi S, Kuma K, Walter Jr RM, Kumagai LF, Nagataki S: Methimazole- induced agranulocytosis in Japanese patients with Graves' disease. Clin Endocrinol 30:525-530, 1989.
146. Amrhein JA, Kenny F, Ross D: Granulocytopenia, lupus-like syndrome, and other complications of propylthiouracil therapy. J Pediatr 76:54, 1970.
147. Pacini F, Sridama V, Refetoff S: Multiple complications of propylthiouracil treatment: Granulocytopenia, eosinophilia, skin reaction, and hepatitis with lymphocyte sensitization. J Endocrinol Invest 5:403-407, 1982.
147.1 Darben T, Savige J, Prentice R, Paspaliaris B, Chick J. 1999 Pyoderma gangrenosum with secondary pyarthrosis following propylthiouracil. Australasian J Dermatol. 40:144-146.
148. Wall JR, Fang SL, Kuroki T, Ingbar SH, Braverman LE: In vitro immunoreactivity to propylthiouracil, methimazole, and carbimazole in patients with Graves' disease: A possible cause of antithyroid drug-induced agranulocytosis. J Clin Endocrinol Metab 58:868-872, 1984.
149. Biswas N, Ahn Y-H, Goldman JM, Schwartz JM: Case report: Aplastic anemia associated with antithyroid drugs. Am J Med Sci 301:190-194, 1991.
149.1 Breier DV, Rendo P, Gonzalez J, Shilton G, Stivel M, Goldztein S. Massive plasmocytosis due to methimazole-induced bone marrow toxicity. Amer J Hematol 67:259-261, 2001.
149.1 Gunton JE, Stiel J, Caterson RJ, McElduff A. Antithyroid drugs and antineutrophil cytoplasmic antibody positive vasculitis. A case report and review of the literature. J Clin Endocrinol Metab 84:13-16, 1999
149.2 Guma M, Salinas I, Reverter JL, Roca J, Valls-Roc M, Juan M, Olive A. Frequency of antineutrophil cytoplasmic antibody in Graves’ disease patients treated with methimazole. J Clin Endocrinol Metab 88:2141-2146, 2003.
150. Tajiri J, Noguchi S, Murakami T, Murakami N: Antithyroid drug-induced agranulocytosis. The usefulness of routine white blood cell count monitoring. Arch Intern Med 150:621- 624, 1990.
151. Cooper DS: Antithyroid drugs. N Engl J Med 311:1353- 1362, 1984.
152. Weiss M, Hassin D, Bank H: Propylthiouracil-induced hepatic damage. Arch Intern Med 140:1184-1185, 1980.
152.1. Williams KV, Nayak S, Becker D, Reyes J, Burmeister LA. Fifty years of experience with propylthiouracil-associated hepatotoxicity: What have we learned? J Clin Endocrinol Metab 82:1727-1733, 1997.
125.2 Majima T, Komatsu Y, Doi K, Takagi C, Shigemoto M, Fukao A, Morimoto T, Corners J, Nakao K.Clinical significance of risedronate for osteoporosis in the initial treatment of male patients with Graves' disease.J Bone Miner Metab. 2006;24(2):105-13.
153. Miyazono K, Okazaki T, Uchida S, Totsuka Y, Matsumoto T, Ogata E, Terakawa K, Kurihara N, Takeda T: Propylthiouracil-induced diffuse interstitial pneumonitis. Arch Intern Med 144:1764-1765, 1984.
153.1. Escobar-Morreale HF, Bravo P, Garcia-Robles R, Garcia-Larana J, de la Calle H, Sancho JM. Methimazole-induced severe aplastic anemia: unsuccessful treatment with recombinant human granulocyte-monocyte colony-stimulating factor. Thyroid 7:67-70, 1997.
153.2 Karlsson, FA; Axelsson, O; Melhus, H. Severe embryopathy and exposure to methimazole in early pregnancy. J Clin Endocrinol Metab 87 947-948 2002.
154. Tamai H, Mukuta T, Matsubayashi S, Fukata S, Komaki G, Kuma K, Kumagai LF, Nagataki S. Treatment of methimazole-induced agranulocytosis using recombinant human granulocyte colony-stimulating factor (rhG-CSF). J Clin Endocrinol Metab 77:1356-1360, 1993.
155. Godley AF, Stanbury JB: Preliminary experience in the treatment of hyperthyroidism with potassium perchlorate. J Clin Endocrinol Metab 14:70, 1954.
156. Krevans JR, Asper SP Jr, Rienhoff WF Jr: Fatal aplastic anemia following use of potassium perchlorate in thyrotoxicosis. J Amer Med Assn 181:162, 1962.
157. Georges JL, Normand JP, Lenormand ME, Schwob J. Life-threatening thyrotoxicosis induced by amiodarone in patients with benign heart disease. European Heart Journal 13:129-132, 1992.
158. Lazarus JH, Addison GM, Richards AR, Owen GM: Treatment of thyrotoxicosis with lithium carbonate. Lancet 2:1160, 1974.
159. Turner JG, Brownlie BEW, Rogers TGH: Lithium as an adjunct to radioiodine therapy for thyrotoxicosis. Lancet 1:614, 1976.
159.1. Mercado M, Mendoza-Zubieta V, Bautista-Osorio R, Espinoza-De Los Monteros AL. Treatment of hyperthyroidism with a combination of methimazole and cholestyramine. J Clin Endocrinol Metab 81:3191-3193, 1996.
160. Reinwein D, Klein E: Der Einfluss des anorganischen Blutjodes auf den Jodumstaz der menschlichen Schilddruse. Acta Endocrinol 35:485, 1960.
161. Thompson WO, Thorp EG, Thompson PK, Cohen AC: The range of effective iodine dosage in exophthalmic goiter. II. The effect on basal metabolism of the daily administration of one-half drop of compound solution of iodine. Arch Intern Med 45:420, 1930.
162. Friend DG: Iodide therapy and the importance of quantitating the dose. N Engl J Med 263:1358, 1960.
165. Emerson CH, Anderson AJ, Howard WJ, Utiger RD: Serum thyroxine and triiodothyronine concentrations during iodide treatment of hyperthyroidism. J Clin Endocrinol Metab 40:33, 1975.
166. Shanks RG, Hadden DR, Lowe DC, McDevitt DB, Montgomery DAD: Controlled trial of propranolol in thyrotoxicosis. Lancet 2:1969.
167. Mazzaferri EL, Reynolds JC, Young RL, Thomas CN, Parasi AF: Propranolol as primary therapy for thyrotoxicosis. Arch Intern Med 136:50, 1976.
168. Wiener L, Stout BD, Cox JW: Influence of beta sympathetic blockade with propranolol on the hemodynamics of hyperthyroidism. Am J Med 46:227, 1969.
169. Saunders J, Hall SEH, Crowther A, Sonksen PH: The effect of propranolol on thyroid hormones and oxygen consumption in thyrotoxicosis. Clin Endocrinol 9:67, 1978.
170. Georges LP, Santangelo RP, Mackin JF, Canary JJ: Metabolic effects of propranolol in thyrotoxicosis. I. Nitrogen, calcium, and hydroxyproline. Metabolism 24:11, 1975.
171. Hadden DR, Montgomery DAD, Shanks RG, Weaver JA: Propranolol and iodine-131 in the management of thyrotoxicosis. Lancet 2:852, 1968.
172. Pimstone N, Marine N, Pimstone B: Beta-adrenergic blockade in thyrotoxic myopathy. Lancet 2:1219, 1968.
173. Smith CS, Howard NJ: Propranolol in treatment of neonatal thyrotoxicosis. J Pediatr 83:1046, 1973.
174. Rosenberg I: Thyroid storm. N Engl J Med 283:1052, 1970.
174a. Fraser T, Green D. Weathering the storm: beta-blockade and the potential for disaster in severe hyperthyroidism. Emergency Med 13:376-380, 2001
174b. Ikram H. Haemodynamic effects of beta-adrenergic blockade in hyperthyroid patients with and without heart failure. Br Med J 1:1505-1507, 1977.
175. Bewsher PD, Pegg CAS, Steward DJ, Lister DA, Michie W: Propranolol in the surgical management of thyrotoxicosis. Ann Surg 180:787, 1974.
176. Canary JJ, Schaaf M, Duffy BJ, Kyle LH: Effects of oral and intramuscular injection of reserpine in thyrotoxicosis. N Engl J Med 257:435, 1957.
177. Moncke C: Treatment of thyrotoxicosis with reserpine. Med Monatsschr Pharm 50:1742, 1955.
178. Lee WY, Bronsky D, Waldenstein SS: Studies of the thyroid and sympathetic nervous system interrelationships: Effect of guanethidine on manifestations of hyperthyroidism. J Clin Endocrinol Metab 22:879, 1962.
179. deGroot WJ, Leonard JJ, Paley HW, Johnson JE, Warren JV: The importance of autonomic integrity in maintaining the hyperkinetic circulatory dynamics of human hyperthyroidism. J Clin Invest 40:1033, 1961.
180. Dillion PT, Babe J, Meloni CR, Canary JJ: Reserpine in thyrotoxic crisis. N Engl J Med 283:1020, 1970.
181. DeGroot LJ, Hoye K: Dexamethasone suppression of serum T3 and T4. J Clin Endocrinol Metab 4:976, 1976.
182. Williams DE, Chopra IJ, Orgiazzi J, Solomon DH: Acute effects of corticosteroids on thyroid activity in Graves' disease. J Clin Endocrinol Metab 41:354, 1975.
183. Witztum JL, Jacobs LS, Schonfeld G: Thyroid hormone and thyrotropin levels in patients placed on colestipol hydrochloride. J Clin Endocrinol Metab 46:838-840, 1978.
184. Boehm TM, Burman KD, Barnes S, Wartofsky L: Lithium and iodine combination therapy for thyrotoxicosis. Acta Endocrinol 94:174, 1980.
185. Sharp B, Reed AW, Tamagna EI, Gefner DL, Hershman JM: Treatment of hyperthyroidism with sodium ipodate (oragraffin) in addition to propylthiouracil and propranolol. J Clin Endocrinol Metab 53:622, 1981. 186. Croxson MS, Hall TD, Nicoloff JT: Combination drug therapy for treatment of hyperthyroid Graves' disease. J Clin Endocrinol Metab 45:623, 1977.
187. Werner SC, Platman SR: Remission of hyperthyroidism (Graves' disease) and altered pattern of serum-thyroxine binding induced by prednisone. Lancet 2:752, 1965.
188. Wu S-Y, Shyh T-P, Chopra IJ, Solomon DH, Huang H-W, Chu P-C: Comparison of sodium ipodate (oragrafin) and propylthiouracil in early treatment of hyperthyroidism. J Clin Endocrinol Metab 54:630, 1982.
189. Shen D-C, Wu S-Y, Chopra IJ, Huang H-W, Shian L-R, Bian T-Y, Jeng C-Y, Solomon DH: Long term treatment of Graves' hyperthyroidism with sodium ipodate. J Clin Endocrinol Metab 61:723, 1985.189.1. Bal CS, Kumar A, Pandey RM. A randomized controlled trial to evaluate the adjuvant effect of lithium on radioiodine treatment of hyperthyroidism. Thyroid 12:399-405, 2002.
190. Hamilton RD, Mayberry WE, McConahey WM, Hanson KC: Ophthalmopathy of Graves' disease: A comparison between patients treated surgically and patients treated with radioiodide. Mayo Clin Proc 42:812, 1967.
191. Arnold MB, Talbot NB, Cope O: Concerning the choice of therapy for childhood hyperthyroidism. Pediatrics 21:47, 1958.
191.1 Erbil Y, Ozluk Y, Giriş M, Salmaslioglu A, Issever H, Barbaros U, Kapran Y, Ozarmağan S, Tezelman S. Effect of lugol solution on thyroid gland blood flow and microvessel density in the patients with Graves' disease.J Clin Endocrinol Metab. 2007 Jun;92(6):2182-9
192. Feek CM, Stewart J, Sawers A, Irvine WJ, Beckett GJ, Ratcliffe WA, Toft AD: Combination of potassium iodide and propranolol in preparation of patients with Graves' disease for thyroid surgery. N Engl J Med 302:883, 1980.
192.1. Kulkarni RS, Braverman LE, Patwardhan NA. Bilateral cervical plexus block for thyroidectomy and parathyroidectomy in healthy and high risk patients. J Endocrinol Invest 19:714-718, 1996.
192.2. Schwartz AE, Clark OH, Ituarte P, Gerfo PL. Thyroid surgery – the choice. J Clin Endocrinol Metab 83:1097-1105, 1998.
193. Bewsher BD, Pegg CAS, Stewart DJ, Lister DA, Michie W: Propranolol in the surgical management of thyrotoxicosis. Ann Surg 180:787, 1974.
194. Toft AD, Irvine WJ, Campbell RWF: Assessment by continuous cardiac monitoring of minimum duration of preoperative propranolol treatment in thyrotoxic patients. Clin Endocrinol 5:195, 1976.
195. Toft AD, Irvine WJ, Sinclair I, McIntosh D, Seth J, Cameron EHD: Thyroid function after surgical treatment of thyrotoxicosis. N Engl J Med 298:643, 1978.195a. Bogazzi F, Miccoli P, Berti P, Cosci C, Brogioni S, Aghini-Lombardi F, Materazzi G, Bartalena L, Pinchera A, Braverman LE, Martino E. Preparation with iopanoic acid rapidly controls thyrotoxicosis in patients with amiodarone-induced thyrotoxicosis before thyroidectomy. Surgery 132:1114-1117, 2002.
196. Taylor GW, Painter NS: Size of the thyroid remnant in partial thyroidectomy for toxic goiter. Lancet 1:287, 1962.
196a. Sugino K, Mimura T, Toshima K, Iwabuchi H, Kitamura Y, Kawano M, Ozaki O, Ito K. Follow-up evaluation of patients with Graves' disease treated by subtotal thyroidectomy and risk factor analysis for post-operative thyroid dysfunction. J Endocrinol Invest 16:195-199, 1993.
196.1. Ozaki O, Ito K, Mimura T, Sugino K, Ito K. Factors affecting thyroid function after subtotal thyroidectomy for Graves’ disease: Case control study by remnant-weight matched-pair analysis. Thyroid 7:555, 1997.
196.2 Schwartz AE, Clark OH, Ituarte P, Lo Gerfo P. Thyroid Surgery- the choice. J Clin. Endo.Metab 83:1097-1105,1998.
197. Colcock BP, King ML: The mortality and morbidity of thyroid surgery. Surg Gynecol Obstet 114:131, 1962.
198. Sawyers JL, Martin CE, Byrd BF Jr, Rosenfield L: Thyroidectomy for hyperthyroidism. Ann Surg 175:939, 1972.
199. Farnell MB, van Heerden JA, McConahey WM, Carpenter HA, Wolff LH Jr: Hypothyroidism after thyroidectomy for Graves' disease. Amer J Surg 142:535, 1981.
200. Klementschitsch P, Shen K-L, Kaplan EL: Reemergence of thyroidectomy as treatment for Graves' disease. Surg Clin North Am 59:35, 1979.
200a. Palit TK, Miller CC, Miltenburg DM. The efficacy of thyroidectomy for Graves' disease: A meta-analysis. J Surg Res 90:161-165, 2000.
201. Winsa B, Rastad J, Akerstrom G, Johansson H, Westermark K, Karlsson FA. Retrospective evaluation of the effect of subtotal and total thyroidectomy in the treatment of Graves' disease with and without endocrine ophthalmopathy. Thesis, Brita Winsa, The University of Upsala, Upsala, Sweden, 1993.201a. Stocker DJ, Foster SS, Solomon BL, Shriver CD, Burch HB. Thyroid cancer yield in patients with Graves’ disease selected for surgery on the basis of cold scintiscan defects. Thyroid 12:305, 2002.
202. Thjodleifsson B, Hedley AJ, Donald D, Chesters MI, Kjed M, Beck JS, Crooks J, Michie W, Hall R: Outcome of subtotal thyroidectomy for thyrotoxicosis in Iceland and Northeast Scotland. Clin Endocrinol 7:367, 1977.
202a: Scholz GH, Hagemann E, Arkenau C, Engelmann L, Lamesch P, Schreiter D,Schoenfelder M, Olthoff D, Paschke R. Is there a place for thyroidectomy in older patients with thyrotoxic storm and cardiorespiratory failure?Thyroid. 2003 Oct;13(10):933-40.
203. Soreide JA, van Heerden JA, Lo CY, Grant CS, Zimmerman D, Ilstrup DM. Surgical treatment of Graves’ disease in patients younger than 18 years. World J Surg 20:794-800, 1996.
203.1 Sherman J, Thompson GB, Lteif A, Schwenk WF 2nd, van Heerden J, Farley DR, Kumar S, Zimmerman D, Churchward M, Grant CS.Surgical management of Graves disease in childhood and adolescence: an institutional experience.Surgery. 2006 Dec;140(6):1056-61
204. Miccoli P, Vitti P, Rago T, Iacconi P, Bartalena L, Bogazzi F, Fiore E, Valeriano R, Chiovato L, Rocchi R, Pinchera A. Surgical treatment of Graves’ disease: Subtotal or total thyroidectomy? Surgery 120:1020-1025, 1996.
204.a Torring O, Tallstedt L, Wallin G, Lundell G, Ljunggren J-G, Taube A, Saaf M, Hamberger B, and The Thyroid Study Group. Graves' hyperthyroidism: Treatment with antithyroid drugs, surgery, or radioiodine-a prospective, randomized study. J Clin Endocrinol Metab 81:2986-2993, 1996.
204b. Moleti M204b. Moleti M, Mattina F, Lo Presti VP, Baldari CS, Bonanno N, Trimarchi F, Vermiglio F. Role of residual thyroid tissue ablation after thyroidectomy for Graves' disease. Its effects on the course of related ophthalmopathy. J Endocrinol Invest 23:37, 2000.
204c. De Bellis A204c. De Bellis A, Bizzarro A, Perrino S, Coronclla C, Iorio S, Pepe M, Guaglione M, Wall JR, Bellastella A. Improvement of severe ophthalmopathy and decrease of antibodies against extraocular muscles, G2s, and Fp subunit of succinate dehydrogenase after near-total thyroidectomy in Graves' disease. J Endocrinol Invest 23:14, 2000.
204d. Marcocci C204d. Marcocci C, Bruno-Bossio G, Manetti L, Tanda ML, Miccoli P, Iacconi P, Bartolomei MP, Nardi M, Pinchera A, Bartalena L. The course of Graves' ophthalmopathy is not influenced by near-total thyroidectomy; a case-control study. Clin Endocrinol 51:503-508, 1999.
204e. Moleti, M; Mattina, F; Salamone, I; Violi, MA; Nucera C; Baldari, S; Schiavo, MGL; Regalbuto, C; Trimarchi, F; Vermiglio, F. Effects of thyroidectomy alone or followed by radioiodine ablation of thyroid remnants on the outcome of Graves’ ophthalmopathy. Thyroid 13 653-658 2003.
204f: Panzer C, Beazley R, Braverman L. Rapid preoperative preparation for severe hyperthyroid Graves' disease.JClin Endocrinol Metab. 2004 May;89(5):2142-4.
204g. Menconi F, Marinò M, Pinchera A, Rocchi R, Mazzi B, Nardi M, Bartalena L, Marcocci C.Effects of total thyroid ablation versus near-total thyroidectomy alone on mild to moderate Graves' orbitopathy treated with intravenous glucocorticoids. J Clin Endocrinol Metab. 2007 May;92(5):1653-8.IN
205. Yamashita H, Noguchi S, Tahara K, Watanabe S, Uchino S, Kawamoto H, Toda M, Murakami N. Postoperative tetany in patients with Graves’ disease: A risk factor analysis. Clin Endocrinol 47:71-77, 1997.
206. Buchanan WW, Koutras DA, Crooks J, Alexander WD, Brass W, Anderson JR, Goudie RB, Gray KG: The clinical significance of the complement-fixation test in thyrotoxicosis. J Endocrinol 24:115, 1962.
207. Michie W, Duncan T, Hamer-Hodges DW, Bewsher PD, Stowers JM, Pegg CAS, Hems G, Hedley AJ: Mechanism of hypocalcemia after thyroidectomy for thyrotoxicosis. Lancet 1:508, 1971.
208. Hardisty CA, Talbot CH, Munro DS: The effect of partial thyroidectomy for Graves' disease on serum long-acting thyroid stimulator protector (LATS-P). Clin Endocrinol 14:181, 1981.
209. Bech K, Feldt-Rasmussen U, Bliddal H, Date J, Blichert-Toft M: The acute changes in thyroid stimulating immunoglobulins, thyroglobulin, and thyroglobulin antibodies following subtotal thyroidectomy. Clin Endocrinol 16:235, 1982.
210. Fukino O, Tamai H, Fujii S, Ohsako N, Matsubayashi S, Kuma K, Nagataki S: A study of thyroid function after subtotal thyroidectomy for Graves' disease: particularly on TRH tests, T3 suppression tests and antithyroid antibodies in euthyroid patients. Acta Endocrinol 103:28-33, 1983.
210.1. Werga-Kjellman P, Zedenius J, Tallstedt L, Traisk F, Lundell G, Wallin G. Surgical treatment of hyperthyroidism: A ten year experience. Thyroid 11:187-192, 2001.
211. Hedley AJ, Hall R, Amos J, Michie W, Crooks J: Serum-thyrotropin levels after subtotal thyroidectomy for Graves' disease. Lancet 1:455, 1971.
211.1 Segni M, Leonardi E, Mazzoncini B, Pucarelli I, Pasquino AM. 1999 Special features of Graves' disease in early childhood. Thyroid 9:871.
212. Hung W, Wilkins L, Blizzard R: Medical therapy of thyro- toxicosis in children. Pediatrics 30:17, 1962.
213. Starr P, Jaffe HL, Oettinger L Jr: Late results of 131I treatment of hyperthyroidism in seventy-three children and adosescents. J Nucl Med 5:81, 1964.
213.1. Perrild H, Jacobsen BB. Thyrotoxicosis in childhood. Europ J Endocrinol 134:678-679, 1996.
214. Kogut MD, Kaplan SA, Collipp PJ, Tiamsic T, Boyle D: Treatment of hyperthyroidism in children. N Engl J Med 272:217, 1965.
214.1. Rivkees SA, Sklar C, Freemark M. The management of Graves’ disease in children, with special emphasis on radioiodine treatment. J Clin Endocrinol Metab 83:3767-3776.
214.11: Read CH Jr, Tansey MJ, Menda Y. A 36-year retrospective analysis of the efficacy and safety of radioactive iodine in treating young Graves' patients. J Clin Endocrinol Metab. 2004 Sep;89(9):4229-33.
215.1. Okuno A, Yano K, Inyaku F, Suzuki Y, Sanae N, Kumai M, Naitoh Y. Pharmacokinetics of methimazole in children and adolescents with Graves’ disease. Acta Endocrinol (Copenh) 115:112-118, 1987.
215.1 Barrio R, Lopez-Capape M, Martinez-Badas I, Carrillo A, Moreno JC, Alonso M.Graves' disease in children and adolescents: response to long-term treatment.Acta Paediatr. 2005 Nov;94(11):1583-9
215.2 Koch CA, Sarlis NJ. The spectrum of thyroid diseases in childhood and its evolution during transition to adulthood: Natural history, diagnosis, differential diagnosis and management. J Endocrinol Invest 24:659-675, 2001.
216. Rudberg C, Johansson H, Akerstrom G, Tuvemo T, Karlsson FA. Graves’ disease in children and adolescents. Late results of surgical treatment. Europ J Endocrinol 134:710-715, 1996.
217.1 Clementi M, Di Gianantonio E, Pelo E, Mammi I, Basile RT, Tenconi R. 1999 Methimazole embryopathy: delineation of the phenotype. Amer J Medical Genet. 83:43-46.
217. Cheek JH, Rezvani I, Goodner D, Hopper B: Prenatal treatment of thyrotoxicosis to prevent intrauterine growth retardation. Obstet Gynecol 60:122, 1982.
217.1 Luton D, Le Gac I, Vuillard E, Castanet M, Guibourdenche J, Noel M, Toubert ME, Leger J, Boissinot C, Schlageter MH, Garel C, Tebeka B, Oury JF, Czernichow P, Polak M.Management of Graves' disease during pregnancy: the key role of fetal thyroid gland monitoring.J Clin Endocrinol Metab. 2005 Nov;90(11):6093-8
218.1 Zimmerman D. 1999 Fetal and neonatal hyperthyroidism. Thyroid 9:727.
218. Jarett SN, Seniour B, Braudo JL, Heymann S: Neonatal thyrotoxicosis. Pediatrics 24:65, 1959.
219. Hollingsworth DR, Mabry CC, Eckerd JM: Hereditary aspects of Graves' disease in infancy and childhood. J Pediatr 81:446, 1972.