Chapter 11
Graves' Disease:
Diagnosis and Treatment
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Table of Contents
Laboratory Diagnosis of Graves' Disease
Serum Hormone Measurements
T
3
Toxicosis
RAIU
Thyroid Scanning
Antithyroid Antibodies
ANTIBODIES TO TSH-RECEPTOR
BMR
Other Assays
Response to KI
Differential Diagnosis
TREATMENT - SELECTION OF METHOD
131-I THERAPY FOR THYROTOXICOSIS OF GRAVES' DISEASE
SELECTION OF 131-I Dosage
Course After Treatment
Problems Associate With
131
I Therapy
Hazards of
131
I Treatment
Carcinogenesis
Leukemia
Genetic Damage
Pregnancy
Treatment of Thyrotoxicosis with Drugs
Long-Term Antithyroid Drug Therapy with Thiocarbamides
Toxic Reactions To Antithyroid Drugs
Potassium Perchlorate and Lithium
Iodine
Use of Drugs in Adjunctive Therapy for Graves' Disease
Surgical Treatment
Preparation for Surgery
Surgical Techniques and Complications
Course After Surgery
Long Term Follow-Up
Special Considerations in the Treatment of Thyrotoxicosis in Children
Therapy of Childhood Graves' Disease
Intrauterine and Neonatal Thyrotoxicosis
General Therapeutic Relationship of the Patient and Physician
SUMMARY