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Chapter 16
Genetic Defects in Thyroid Hormone Supply, Thyroid Hormone Resistance Syndrome, Abnormalities of Thyroid Hormone Transport
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arrow.gif CLINICAL CLASSIFICATION
arrow.gif INCIDENCE AND INHERITANCE
arrow.gif ETIOLOGY AND GENETICS
arrow.gif MOLECULAR BASIS OF THE DEFECT
dot.gif Thyroid Hormone Action at the Gene Level
dot.gif Properties of Mutant TRß Receptors and Dominant Negative Effect
arrow.gif MOLECULAR BASIS OF THE VARIABLE PHENOTYPE OF RTH
arrow.gif RTH WITHOUT TR GENE MUTATIONS (nonTR-RTH)
arrow.gif ANIMAL MODELS OF RTH
dot.gif TRß Gene Manipulations
dot.gif The Phenotype of TR
arrow.gif PATHOGENESIS
arrow.gif PATHOLOGY
arrow.gif CLINICAL FEATURES
arrow.gif COURSE OF THE DISEASE
arrow.gif LABORATORY FINDINGS
dot.gif Thyroid Hormone and its Metabolites in Serum
dot.gif Thyrotropin and Other Thyroid Stimulators
dot.gif Thyroid Gland Activity and Integrity of Hormone Synthesis
dot.gif Turnover of Thyroid Hormone
dot.gif In-vivo Effects of Thyroid Hormone
dot.gif Other Endocrine Tests
dot.gif Bone age
dot.gif In vitro Tests of Thyroid Hormone Action
arrow.gif RESPONSES TO THE ADMINISTRATION OF THYROID HORMONE
arrow.gif EFFECTS OF OTHER DRUGS
arrow.gif DIFFERENTIAL DIAGNOSIS
arrow.gif TREATMENT