1. Refetoff S. Inherited thyroxine-binding globulin (TBG) abnormalities in man. Endocr. Rev. 10: 275-293, 1989.

2. Chan V, Besser GM, Landon J. Effects of oestrogen on urinary thyroxine excretion. Brit. Med. J. 4: 699-701, 1972.

3. Refetoff S, Robin NI, Fang VS. Parameters of thyroid function in serum of 16 selected vertebrate species: A study of PBI, serum T4, free T4, and the pattern of T4 and T3 binding to serum proteins. Endocrinol. 86: 793-805, 1970.

4. Mendel CM, Weisinger RA, Jones AL, Cavalieri RR. Thyroid hormone-binding proteins in plasma facilitate uniform distribution of thyroxine within tissues: A perfused rat liver study. Endocrinol. 120: 1742-1749, 1987.

5. Pemberton PA, Stein PE, Pepys MB, Potter JM, Carell RW. Hormone binding globulins undergo serpin conformational change in inflammation. Nature 336: 257-258, 1988.

6. Jirasakuldech B, Schussler GC, Yap MG, Drew H, Josephson A, Michl J. A characteristic serpin cleavage product of thyroxine-binding globulin appears in sepsis sera. J. Clin. Endocrinol. Metab. 85: 3996-3999, 2000.

7. Farer LS, Robbins J, Blumberg BS, Rall JE. Thyroxine-serum protein complexes in various animals. Endocrinol. 70: 686-696, 1962.

8. Oppenheimer JH. Role of plasma proteins in the binding, distribution, and metabolism of the thyroid hormones. N. Engl. J. Med. 278: 1153-1162, 1968.

9. Freeman T, Pearson JD. The use of quantitative immunoelectrophoresis to investigate thyroxine-binding human serum proteins. Clin. Chim. Acta 26: 365-368, 1969.

10. Benvenga S, Gregg RE, Robbins J. Binding of thyroid hormone to human plasma lipoproteins. J. Clin. Endocrinol. Metab. 67: 6-16, 1988.

11. Beierwaltes WH, Robbins J. Familial increase in the thyroxine-binding sites in serum alpha globulin. J. Clin. Invest. 38: 1683-1688, 1959.

12. Mori Y, Seino S, Takeda K, Flink IL, Murata Y, Bell GI, Refetoff S. A mutation causing reduced biological activity and stability of thyroxine-binding globulin probably as a result of abnormal glycosylation of the molecule. Mol. Endocrinol. 3: 575-579, 1989.

13. Robbins J. Thyroxine transport and the free hormone hypothesis. J. Clin. Endocrinol. Metab. 131: 546-547, 1992.

14. Flink IL, Bailey TJ, Gustefson TA, Markham BE, Morkin E. Complete amino acid sequence of human thyroxine-binding globulin deduced from cloned DNA: Close homology to the serine antiproteases. Proc. Natl. Acad. Sci. (USA) 83: 7708-7712, 1986.

15. Zhou A, Wei Z, Read RJ, Carrell RW. Structural mechanism for the carriage and release of thyroxine in the blood. Proc Natl Acad Sci U S A 103: 13321-13326, 2006.

16. AprMurata Y, Magner J, Refetoff S. The role of glycosylation in the molecular conformation and secretion of thyroxine-binding globulin. Endocrinol. 118: 1614-1621, 1986.

17. Kambe F, Seo H, Mori Y, Murata Y, Janssen OE, Refetoff S, Matsui N. An additional carbohydrate chain in the variant thyroxine-binding globulin-Gary (TBGAsn-96) impairs its secretion. Mol. Endocrinol. 6: 443-449, 1992.

18. Gärtner R, Henze R, Horn K, Pickardt CR, Scriba PC. Thyroxine-binding globulin: Investigation of microheterogeneity. J Clin Endocrinol Metab 52: 657-664, 1981.

19. Refetoff S, Fang VS, Marshall JS. Studies on human thyroxine-binding globulin (TBG): IX. Some physical, chemical and biological properties of radioiodinated TBG and partially desialylated TBG (STBG). J Clin Invest 56: 177-187, 1975.

20. Grimaldi S, Edelhoch H, Robbins J. Effects of thyroxine binding on the stability, conformation, and fluorescence properties of thyroxine-binding globulin. Biochem. 21: 145-150, 1982.

21. Refetoff S, Murata Y, Vassart G, Chandramouli V, Marshall JS. Radioimmunoassays specific for the tertiary and primary structures of thyroxine-binding globulin (TBG): Measurement of denatured TBG in serum. J. Clin. Endocrinol. Metab. 59: 269-277, 1984.

22. Tabachnick M, Giorgio NA, Jr. Thyroxine-protein interactions. II. The binding of thyroxine and its analogues to human serum albumin. Arch. Biochem. Biophys. 105: 563-569, 1964.

23. Refetoff S, Hagen S, Selenkow HA. Estimation of the T4 binding capacity of serum TBG and TBPA by a single T4 load ion exchange resin method. J. Nucl. Med. 13: 2-12, 1972.

24. Grasberger H, Golcher HM, Fingerhut A, Janssen OE. Loop variants of the serpin thyroxine-binding globulin: implications for hormone release upon limited proteolysis. Biochem. J. 365: 311-316, 2002.

25. Trent JM, Flink IL, Morkin E, Van Tuinen P, Ledbetter DH. Localization of the human thyroxine-binding globulin gene to the long arm of the X chromosome (Xq21-22). Am. J. Hum. Genet. 41: 428-435, 1987.

26. Mori Y, Miura Y, Oiso Y, Seo H, Takazumi K. Precise localization of the human thyroxine-binding globulin gene to chromosome Xq22.2 by fluorescence in situ hybridization. Hum. Genet. 96: 481-482, 1995.

27. Hayashi Y, Mori Y, Janssen OE, Sunthornthepvarakul T, Weiss RE, Takeda K, Weinberg M, Seo H, Bell GI, Refetoff S. Human thyroxine-binding globulin gene: Complete sequence and transcriptional regulation. Mol. Endocrinol. 7: 1049-1060, 1993.

28. Hocman G. Human thyroxine binding globulin. Rev Physiol Biochem Pharmacol 81: 45-88, 1981.

29. Cody V. Thyroid hormone interactions: Molecular conformation, protein binding and hormone action. Endocr. Rev. 1: 140-166, 1980.

30. Oppenheimer JH, Tavernetti RR. Displacement of thyroxine from human thyroxine-binding globulin by analogues of hydantoin. Steric aspects of the thyroxine-binding site. J. Clin. Invest. 41: 2213-2220, 1962.

31. Larsen PR. Salicylate-induced increases in free triiodothyronine in human serum: Evidence of inhibition of triiodothyronine binding to thyroxine-binding gloublin and thyroxine-binding prealbumin. J. Clin. Invest. 51: 1125-1134, 1972.

32. Janssen OE, Golcher HMB, Grasberger H, Saller B, Mann K, Refetoff S. Characterization of thyroxine-binding globulin cleaved by human leukocyte elastase. J. Clin. Endocrinol. Metab. 87: 1217-1222, 2002.

33. Cavalieri RR, McMahon FA, Castle JN. Preparation of 125I-labeled human thyroxine-binding alpha globulin and its turnover in normal and hypothyroid subjects. J Clin Invest 56: 79-87, 1975.

34. Refetoff S, Fang VS, Marshall JS, Robin NI. Metabolism of thyroxine-binding globulin (TBG) in man: Abnormal rate of synthesis in inherited TBG deficiency and excess. J. Clin. Invest. 57: 485-495, 1976.

35. Andreoli M, Robbins J. Serum proteins and thyroxine-protein interaction in early human fetuses. J. Clin. Invest. 41: 1070-1077, 1962.

36. Robbins J, Nelson JH. Thyroxine-binding by serum protein in pregnancy and in the newborn. J. Clin. Invest. 37: 153-159, 1958.

37. Stubbe P, Gatz J, Heidemann P, Muhlen ARG, Hesch R. Thyroxine-binding globulin, triiodothyronine, thyroxine and thyrotropin in newborn infants and children. Horm. Metab. Res. 10: 58-61, 1978.

38. Braverman LE, Dawber NA, Ingbar SH. Observations concerning the binding of thyroid hormones in sera of normal subjects of varying ages. J. Clin. Invest. 45: 1273-1279, 1966.

39. Burman KD, Read J, Dimond RC, Strum D, Wright FD, Patow W, Earll JM, Wartofsky L. Measurement of 3,3',5'-Triiodothyroinine (reverse T3), 3,3'-L-diiodothyronine, T3 and T4 in human amniotic fluid and in cord and maternal serum. J Clin Endocrinol Metab 43: 1351-1359, 1976.

40. Hagen GA, Elliott WJ. Transport of thyroid hormones in serum and cerebrospinal fluid. J Clin Endocrinol Metab 37: 415-422, 1973.

41. Gavin LA, McMahon FA, Castle JN, Cavalieri RR. Detection of a thyroxine-binding protein physicochemically similar to serum thyroxine-binding globulin in normal human urine. J Clin Endocrinol Metab 48: 843-847, 1979.

42. Doe RP, Mellinger GT, Swaim WR, Seal JS. Estrogen dosage effects on serum proteins: A longitudinal study. J. Clin. Endocrinol. Metab. 27: 1081-1086, 1967.

43. Ain KB, Mori Y, Refetoff S. Reduced clearance rate of thyroxine-binding globulin (TBG) with increased sialylation: A mechanism for estrogen induced elevation of serum TBG concentration. J. Clin. Endocrinol. Metab. 65: 689-696, 1987.

44. Ain KB, Refetoff S. Relationship of oligosaccharide modification to the cause of serum thyroxine-binding globulin excess. J. Clin. Endocrinol. Metab. 66: 1037-1043, 1988.

45. Federman DD, Robbins J, Rall JE. Effects of methyl testosterone on thyroid function, thyroxine metabolism, and thyroxine-binding protein. J. Clin. Invest. 37: 1024-1030, 1958.

46. Barbosa J, Seal US, Doe RP. Effects of anabolic steroids on hormone-binding proteins, serum cortisol and serum nonprotein-bound cortisol. J. Clin. Endocrinol. Metab. 32: 232-240, 1971.

47. Braverman LE, Foster AE, Ingbar SH. Sex-related differences in the binding in serum of thyroid hormone. J. Clin. Endocrinol. Metab. 27: 227-232, 1967.

48. Bartalena L, Farsetti A, Flink IL, Robbins J. Effects of interleukin-6 on the expression of thyroid-hormone binding protein genes in cultured hepatoblastoma-derived (Hep G2) cells. Mol. Endocrinol. 6: 935-942, 1992.

49. Marshall JS, Pensky J, Green AM. Studies on human thyroxine-binding globulin. IV. The nature of slow thyroxine-binding globulin. J Clin Invest 51: 3173-3181, 1972.

50. Reilly CP, Wellby ML. Slow thyroxine binding globulin in the pathogenesis of increased dialysable fraction of thyroxine in nonthyroidal illnesses. J. Clin. Endocrinol. Metab. 57: 15-18, 1983.

51. Marshall JS, Green AM, Pensky J, Williams S, Zinn A, Carlson DM. Measurement of circulating desialylated glycoproteins and correlation with hepatocellular damage. J. Clin. Invest. 54: 555-562, 1974.

52. Macchia PE, Harrison HH, Scherberg NH, Sunthornthepvarakul T, Jaeken J, Refetoff S. Thyroid function tests and characterization of thyroxine-binding globulin in the carbohydrate-deficient glycoprotein syndrome type I. J. Clin. Endocrinol. Metab. 80: 3744-3749, 1995.

53. Jaeken J, Hagberg B, Strømme P. Clinical presentation and natural course of the carbohydrate-deficient glycoprotein syndrome. Acta Pediatr. Scand. Suppl 375: 6-13, 1991.

54. Stibler H, Jaeken J, Kristiansson B. Biochemical characteristics and diagnosis of the carbohydrate-deficient glycoprotein syndrome. Acta Pediatr Scand Suppl 375: 21-31, 1991.

55. Ingbar SH. A thyroxine-binding protein of human plasma. Endocrinol. 63: 256-259, 1958.

56. Kanai M, Raz A, Goodman D. Retinol-binding protein: The transport protein for vitamin A in human plasma. J Clin Invest 47: 2025-2044, 1968.

57. Peterson PA. Characteristics of a vitamin A-transporting protein complex occurring in human serum. J Biol Chem 246: 34-43, 1971.

58. Tsuzuki T, Mita S, Maeda S, Araki S, Shimada K. Stucture of human prealbumin gene. J. Biol. Chem. 260: 12224-12227, 1985.

59. Alper CA, Robin NI, Refetoff S. Genetic polymorphism of Rhesus thyroxine-binding prealbumin: Evidence for tetrameric structure in primates. Proc. Natl. Acad. Sci. (USA) 63: 775-781, 1969.

60. Bernstein RS, Robbins J, Rall JE. Polymorphism of monkey thyroxine-binding prealbumin (TBPA): Mode of inheritance and hybridization. Endocrinol. 86: 383-390, 1970.

61. Rerat C, Schwick HG. Données cristallographiques sur la préalbumine du plasma sanguin. Acta Cryst. 22: 441, 1967.

62. Blake CCF, Oatley SJ. Protein-DNA and protein-hormone interactions in prealbumin: A model of the thyroid hormone nuclear receptor? Nature (London) 268: 115-120, 1977.

63. Irace G, Edelhoch H. Thyroxine induced conformational changes in prealbumin. Biochem. 17: 5729-5733, 1978.

64. van Jaarsveld PP, Edelhoch H, Goodman DS, Robbins J. The interaction of human plasma retinol binding protein with prealbumin. J. Biol. Chem. 248: 4698-4705, 1973.

65. LeBeau MM, Geurts van Kessel G. Report of the committee on the genetic costitution of chromosome 18. Cytogenet. Cell. Genet. 58: 739-750, 1991.

66. Costa RH, Grayson DR, Darnell Jr JE. Multiple hepatocyte-enriched nuclear factors function in the regulation of transthyretin and ¿1-antitrypsin. Mol. Cell. Biol. 9: 1415-1425, 1989.

67. Sladeck FM, Zhong R, Lai E, Darnell Jr. JE. Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily. Gene Dev. 4: 2353-2365, 1990.

68. Knowles BB, Howe CC, Aden DP. Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen. Science 209: 497-499, 1980.

69. Dickson PW, ., Howlett GJ, Schreiber G. Rat transthyretin (prealbumin): molecular cloning, nucleotide sequence, and gene expression in liver and brain. J. Biol. Chem. 260: 8214-, 1985.

70. Dickson PW, Aldred AR, Marley PD, Bannister D. Rat choroid plexus specializes in the synthesis and secretion of transthyretin (prealbumin). J. Biol. Chem. 261: 3475-, 1985.

71. Jacobsson B, Pettersson T, Sandstedt B, Carlstrom A. Prealbumin in the islets of Langerhans. Int. Res. Commun. Syst. Med. Sci. 7: 590-, 1979.

72. Herbert J, Wilcox JN, Pham K-TC, Fremeau Jr RT, Zeviani M, Dwork A, Soprano DR, Makover A, Goodman DS, Zimmerman EA, Roberts JL, Schon EA. Transthyretin: a choroid plexus-specific transport protein in human brain. Neurology 36: 900-911, 1986.

73. Woeber KA, Ingbar SH. The contribution of thyroxine-binding prealbumin to the binding of thyroxine in human serum, as assessed by immunoadsorption. J. Clin. Invest. 47: 1710-1721, 1968.

74. Pages RA, Robbins J, Edelhoch H. Binding of thyroxine and thyroxine analogs to human serum prealbumin. Biochem. 12: 2773-2779, 1973.

75. Lueprasitsakul W, Alex S, Fang SL, Pino S. Flavonoid administration immediately displaces thyroxine (T4) from serum transthyretin, increases serum free T4, and decreases thyrotropin in the rat. Endocrinol. 126: 2890-, 1990.

76. Wolff J, Standaert ME, Rall JE. Thyroxine displacement from serum proteins and depression of serum protein-bound iodine by certain drugs. J. Clin. Invest. 40: 1373-1379, 1961.

77. Munro SL, Lim CF, Hall JG, Barlow JW, Craik DJ, Topliss DJ, Stockigt JR. Drug competition for thyroxine binding to transthyretin (Prealbumin): Comparison with effects on thyroxine-binding globulin. J. Clin. Endocrinol. Metab. 68: 1141-1147, 1989.

78. Socolow EL, Woeber KA, Purdy RH, Holloway MT, Ingbar SH. Preparation of I131-labeled human serum prealbumin and its metabolism in normal and sick patients. J. Clin. Invest. 44: 1600, 1965.

79. Oppenheimer JH, Surks MI, Bernstein G, Smith JC. Metabolism of iodine-131-labeled thyroxine-binding prealbumin in man. Science 149: 748-751, 1965.

80. Braverman LE, AvRuskin T, Cullen MJ, Vagenakis AG, Ingbar SH. Effects of norethandrolone on the transport and peripheral metabolism of thyroxine in patients lacking thyroxine-binding globulin. J. Clin. Invest. 50: 1644-1649, 1971.

81. Braverman LE, Ingbar SH. Effects of norethandrolone on the transport in serum and peripheral turnover of thyroxine. J. Clin. Endocrinol. Metab. 27: 389-396, 1967.

82. Oppenheimer JH, Werner SC. Effect of prednisone on thyroxine-binding proteins. J. Clin. Endocrinol. Metab. 26: 715-721, 1966.

83. Man EB, Reid WA, Hellegers AE, Jones WS. Thyroid function in human pregnancy. III. Serum thyroxine-binding prealbumin (TBPA) and thyroxine-binding globulin (TBG) of pregnant women aged 14 through 43 years. Am. J. Obst. Gyn. 103: 338-347, 1969.

84. Inada M, Sterling K. Thyroxine turnover and transport in Laennec's cirrhosis of the liver. J. Clin. Invest. 46: 1275-1282, 1967.

85. Ingenbleek Y, deVisscher M, deNayer P. Measurement of prealbumin as index of protein-calorie malnutrition. Lancet 2: 106-108, 1972.

86. Smith FR, Underwood BA, Denning CR, Varma A, Goodman DSC. Depressed plasma retinol-binding protein levels in cystic fibrosis. J. Lab. Clin. Med. 80: 423-433, 1972.

87. Rajatanavin R, Liberman C, Lawrence GD, D'Arcangues CM, Young RA, Emerson CH. Euthyroid hyperthyroxinemia and thyroxine-binding prealbumin excess in islet cell carcinoma. J. Clin. Endocrinol. Metab. 61: 17-21, 1985.

88. Peters T, Jr. Serum albumin. Adv. Prot. Chem. 37: 161-245, 1985.

89. Murray JC, Van Ommen GJB. Report of the committee on the genetic constitution of chromosome 4. Cytogenet. Cell. Genet. 58: 231-260, 1991.

90. Dugaiczyk A, Law SW, Dennison OE. Nucleotide sequence and the encoded amino acids of human serum albumin mRNA. Proc. Natl. Acad. Sci. (USA) 79: 71-75, 1982.

91. Hayashi Y, Chan J, Nakabayashi H, Hashimoto T, Tamaoki T. Identification and characterization of two enhancers of the human albumin gene. J. Biol. Chem. 267: 14580-14585, 1992.

92. Gereghini S, Raymondjean M, Carranca AG, Heibomel P, Yaniv M. Factors involved in control of tissue-specific expression of albumin gene. Cell 50: 627-638, 1987.

93. Johnson PF. Transcriptional activators in hepatocytes. Cell Growth Differ. 1: 47-52, 1990.

94. Rey-Campos J, Yaniv M. Regulation of albumin gene expression. Amsterdam: Elsevier Science Publishers, 1992.

95. Tabachnick M. Thyroxine-protein interactions. III. Effect of fatty acids, 2,4-dinitrophenol and other anionic compounds on the binding of thyroxine by human serum albumin. Arch. Biochem. Biophys. 106: 415-421, 1964.

96. Beeken WL, Volwilier W, Goldsworthy PD, Garby LE, Reynolds WE, Stogsdill R, Stemler RS. Studies of I131-albumin catabolism and distribution in normal young male adults. J. Clin. Invest. 41: 1312-1333, 1962.

97. Pietrangelo A, Panduro A, Chowdhury JR, Shafritz DA. Albumin gene expression is down-regulated by albumin or macromolecule infusion in the rat. J. Clin. Invest. 89: 1755-1760, 1992.

98. Hollander CS, Bernstein G, Oppenheimer JH. Abnormalities of thyroxine binding in analbuminemia. J. Clin. Endocrinol. Metab. 28: 1064-1066, 1968.

99. Benvenga S, Robbins J. Lipoprotein-thyroid hormone interactions. TEM 4: 194-198, 1993.