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Chapter 6e
Evaluation of Thyroid Function in Health and Disease

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 EVALUATION BY LABORATORY TESTS
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 In Vivo Tests of Thyroid Gland Activity and Integrity of Hormone Synthesis and Secretion
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 Thyroidal Radioiodide Uptake (RAIU)
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 Early Thyroid RAIU and 99mPertechnetate Uptake Measurements
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Perchlorate Discharge Test
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Measurement of Hormone Concentration and Other Iodinated Compounds and Their Transport in Blood
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Measurement of Total and Unsaturated Thyroid Hormone-Binding Capacity in Serum
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Estimation of Free Thyroid Hormone Concentration
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Measurements of Iodine-Containing Hormone Precursors and Products of Degradation
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Measurement of Thyroid Hormone and Its Metabolites in Other Body Fluids and in Tissues
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 Tests Assessing the Effects of Thyroid Hormone on Body Tissues
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 Basal Metabolic Rate (BMR)
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 Deep Tendon Reflex Relaxation Time (Photomotogram)
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 Tests Related to Cardiovascular Function
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Miscellaneous Biochemical and Physiologic Changes Related to the Action of Thyroid Hormone on Peripheral Tissues
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 Measurement of Substances Absent in Normal Serum
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Thyroid Autoantibodies
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 Thyroid-Stimulating Immunoglobulins (TSI)
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 Other Substances with Thyroid-Stimulating Activity
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 Tests of Cell-Mediated Immunity (CMI)
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 Biopsy of the Thyroid Gland
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 Evaluation of the Hypothalamic-Pituitary-Thyroid Axis
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 Thyrotropin (TSH)
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 Thyrotropin-Releasing Hormone (TRH)
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 TRH Test
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 Thyroid Suppression Test
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 Specialized Thyroid Tests
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 Iodotyrosine Deiodinase Activity
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 Test for Defective Hormonogenesis
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 Iodine Kinetic Studies
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 Absorption of Thyroid Hormone
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 Turnover Kinetics of T4 and T3
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 Metabolic Kinetics of Thyroid Hormones and Their Metabolites
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 Measurement of the Production Rate and Metabolic Kinetics of Other Compounds
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 Transfer of Thyroid Hormone from Blood to Tissues

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