A stimulatory thyrotropin receptor antibody enhances hyaluronic Acid synthesis in graves’ orbital fibroblasts: inhibition by an igf-I receptor blocking antibody. Kumar S, Iyer S, Bauer H, Coenen M, Bahn RS. JCEM 2012 May;97(5):1681- Graves’ ophthalmopathy (GO) is characterized by expanded volume of the orbital fat and extraocular muscle tissues and elevated levels of TSH receptor [...]
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Elisei R, Romei C, Renzini G, Bottici V, Cosci B, Molinaro E, Agate L, Cappagli V, Miccoli P, Berti P, Faviana P, Ugolini C, Basolo F, Vitti P, Pinchera A. The Timing of Total Thyroidectomy in RET Gene Mutation Carriers Could Be Personalized and Safely Planned on the Basis of Serum Calcitonin: 18 Years Experience [...]
Lazarus JH, Bestwick JP, Channon S, Paradice R, Maina A, Rees R, Chiusano E, John R, Guaraldo V, George LM, Perona M,
Need for thyroidectomy in patients treated with radioactive iodide for benign thyroid disease.Villadsen MJ, Sørensen CH, Godballe C, Nygaard B. Dan Med Bull. 2011 Dec;58(12):A4343. ABSTRACT-Nodular toxic and non-toxic goitres are seen in approximately 15% of Danish women, and the pros and cons of thyroidectomy versus radioiodine (RI) therapy are often discussed. The purpose of [...]
Outpatient Thyroid Remnant Ablation Using Repeated Low 131-Iodine Activities (740 MBq/20 mCi x 2) in Patients with Low-Risk Differentiated Thyroid Cancer. Clerc J, Bienvenu-Perrard M, Pichard de Malleray C, Dagousset F, Delbot T, Dreyfuss M, Groussin L, Marlowe RJ, Leger FA, Chevalier A. J Clin Endocrinol Metab. 2012 Jan 11. ABSTRACT- In low-risk differentiated thyroid [...]
Outpatient Thyroid Remnant Ablation Using Repeated Low 131-Iodine Activities (740 MBq/20 mCi x 2) in Patients with Low-Risk Differentiated Thyroid Cancer. Clerc J, Bienvenu-Perrard M, Pichard de Malleray C, Dagousset F, Delbot T, Dreyfuss M, Groussin L, Marlowe RJ, Leger FA, Chevalier A. J Clin Endocrinol Metab. 2012 Jan 11. ABSTRACT- In low-risk differentiated thyroid [...]
Not the Number but the Location of Lymph Nodes Matters for Recurrence Rate and Disease-Free Survival in Patients with Differentiated Thyroid Cancer. de Meer SG, Dauwan M, de Keizer B, Valk GD, Borel Rinkes IH, Vriens MR. World J Surg. 2012 Jan 20. ABSTRACT-Several Japanese studies have focused on identifying prognostic factors in patients with [...]
A Mutation in the Thyroid Hormone Receptor Alpha Gene.Bochukova E, Schoenmakers N, Agostini M, Schoenmakers E, Rajanayagam O, Keogh JM, Henning E, Reinemund J, Gevers E, Sarri M, Downes K, Offiah A, Albanese A, Halsall D, Schwabe JW, Bain M, Lindley K, Muntoni F, Khadem FV, Dattani M, Farooqi IS, Gurnell M, Chatterjee K. N [...]
TOPIC: Prenatal multivitamin pills Title: Iodine Content of U.S. Prenatal Multivitamins Authors: Leung AM, Braverman LE, Pino S, He X, & Pearce EN. Reference: Thyroid 18 (Suppl. 1) S-45, 2008 Abstract of a poster presented at the 79th Annual Meeting of the American Thyroid Association (Chicago, October 2008) Summary Background Adequate maternal iodine intake during [...]
Valle LA , Kloos RT The prevalence of occult medullary thyroid carcinoma at autopsy. J Clin Endocrinol Metab. 2011 Jan;96(1):E109-13. Epub 2010 Oct 13. The prevalence of occult medullary thyroid carcinoma (MTC) in the general population is unknown but may be important when considering strategies to diagnose clinically relevant MTC in nodular goiter or other [...]
James C. Sisson, John Freitas, Iain Ross McDougall, Lawrence T. Dauer, James R. Hurley, James D. Brierley, Charlotte H. Edinboro, David Rosenthal, Michael J. Thomas, Jason A Wexler, Ernest Asamoah, Anca M. Avram, Mira Milas, Carol Greenlee Thyroid. April 2011, 21(4): 335-346. The Most Commonly Occurring Papillary Thyroid Cancer in the United States Is Now [...]
Bahn RS , Castro MR J Clin Endocrinol Metab. 2011 May;96(5):1202-12. Thyroid nodules are very common, and although the majority are benign, approximately 5% may harbor malignancy. The evaluation of the patient with solitary thyroid nodule is generally straightforward and will typically include measurement of serum TSH to assess thyroid function and fine-needle aspiration biopsy [...]
Spencer C , Petrovic I , Fatemi S J Clin Endocrinol Metab. 2011 May;96(5):1283-91. Specimens have thyroglobulin antibody (TgAb) measured prior to thyroglobulin (Tg) testing because the qualitative TgAb status (positive or negative) determines risk for Tg assay interference, and the quantitative TgAb concentration serves as a surrogate tumor marker for differentiated thyroid cancer. This [...]
LINK Bahn RS, Burch HB, Cooper DS, Garber JR, Greenlee MC, Klein I, Laurberg P, McDougall IR, Montori VM, Rivkees SA, Ross DS, Sosa JA, Stan MN. Thyroid. 2011 Apr 21. [PMID21510801) Thyroid Antibody Positivity in the First Trimester of Pregnancy Is Associated with Negative Pregnancy Outcomes. Negro R , Schwartz A , Gismondi R [...]
Yim JH , Kim WB , Kim EY , Kim WG , Kim TY , Ryu JS , Gong G , Hong SJ , Shong YK J Clin Endocrinol Metab April, 2011 The primary treatment of locoregionally recurrent/persistent papillary thyroid cancer (PTC) is surgical removal by reoperation. This study evaluated the efficacy of the first [...]
J Clin Endocrinol Metab. 2011 Feb;96(2):320-32. Epub 2011 Jan 14 Department of Medicine, Gutenberg University Medical Center, Langenbeckstrasse 1, Mainz 55131, Germany. Zang S, Ponto KA, Kahaly GJ. The administration of iv glucocorticoid pulses has been advocated as a treatment approach for patients with inflammatory and moderate to severe Graves’ orbitopathy (GO). This review offers [...]
High rate of persistent hypothyroidism in a large-scale prospective study of postpartum thyroiditis in southern Italy. Stagnaro-Green A , Schwartz A , Gismondi R , Tinelli A , Mangieri T , Negro R . J Clin Endocrinol Metab. 2011 ,96(3):652-7. Limited data exist concerning the hormonal status of women with PPT at the end of [...]
Mitchell CS , Savage DB , Dufour S , Schoenmakers N , Murgatroyd P , Befroy D , Halsall D , Northcott S , Raymond-Barker P , Curran S , Henning E , Keogh J , Owen P , Lazarus J , Rothman DL , Farooqi IS , Shulman GI , Chatterjee K , Petersen [...]
Chambon G , Alovisetti C , Idoux-Louche C , Reynaud C , Rodier M , Guedj AM , Chapuis H , Lallemant JG , Lallemant B The use of preoperative routine measurement of basal serum thyrocalcitonin in candidates for thyroidectomy due to nodular thyroid disorders: results from 2733 consecutive patients. The preoperative routine measurement of [...]
Vadiveloo T , Donnan PT , Cochrane L , Leese GP The Thyroid Epidemiology, Audit, and Research Study (TEARS): the natural history of endogenous subclinical hyperthyroidism. J Clin Endocrinol Metab. 2011 Jan;96(1):E1-8. Epub 2010 Oct 6. This study was to define the rates of progression from subclinical hyperthyroidism (SH) to frank hyperthyroidism and normal thyroid [...]
Levels of neonatal thyroid hormone in preterm infants and neurodevelopmental outcome at 5 1/2 years: millennium cohort study. Delahunty C , Falconer S , Hume R , Jackson L , Midgley P , Mirfield M , Ogston S , Perra O , Simpson J , Watson J , Willatts P , Williams F ; Scottish [...]
Papillary Thyroid Cancer Study Group . Durante C , Attard M , Torlontano M , Ronga G , Monzani F , Costante G , Ferdeghini M , Tumino S , Meringolo D , Bruno R , De Toma G , Crocetti U , Montesano T , Dardano A , Lamartina L , Maniglia A , [...]
Prophylactic central neck dissection and local recurrence in papillary thyroid cancer: a meta-analysis. Zetoune T , Keutgen X , Buitrago D , Aldailami H , Shao H , Mazumdar M , Fahey TJ 3rd , Zarnegar R Ann Surg Oncol. 2010 Dec;17(12):3287-93. The effectiveness of prophylactic central neck dissection (pCND) in the treatment of patients [...]
Real-time elastosonography: useful tool for refining the presurgical diagnosis in thyroid nodules with indeterminate or nondiagnostic cytology. Rago T , Scutari M , Santini F , Loiacono V , Piaggi P , Di Coscio G , Basolo F , Berti P , Pinchera A , Vitti P . J Clin Endocrinol Metab. 2010 Dec;95(12):5274-80. Epub [...]
Thyroid cancer recurrence in patients clinically free of disease with undetectable or very low serum thyroglobulin values. Kloos RT J Clin Endocrinol Metab. 2010 Dec;95(12):5241-8. Epub One hundred seven patients had initial thyroid cancer surgery and subsequent remnant radioiodine ablation. Patients underwent recombinant human TSH (rhTSH)-mediated diagnostic whole-body scan and rhTSH-stimulated thyroglobulin (Tg) measurement before [...]