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Figure 17-2. Heterogeneity of morphology and function in a human multinodular goiter. Autoradiographs of two different areas of typical multindular euthyroid human goiter excised after administration of radioiodine tracer to the patient. There are enormous differences of size, shape and function among the individual follicles of the same goiter. Note also that there is no correlation between the size or any other morphological hallmark of a single follicle and its iodine uptake. (with permission ref.15).