CHAPTERS

ANATOMY AND PHYSIOLOGY
1. Ontogeny, Anatomy, Metabolism and Physiology of the Thyroid	Jacques Dumont, MD, Carine Maenhaut, D Christophe, Gilbert Vassart, MD, P.P. Roger and Robert Opitz
2. Thyroid Hormone Synthesis and Secretion	Bernard Bernard A. Rousset, PhD, Corinne Dupuy, Françoise Miot, Ph.D. and Jacques Dumont, MD
3. Thyroid Hormone Serum Transport Proteins	Samuel Refetoff, MD
4. Cellular Uptake of Thyroid Hormones	Theo J. Visser, PhD
5. Metabolism of Thyroid Hormone	Robin P. Peeters, M.D. PhD and Theo J. Visser, PhD
6. Cellular Action of Thyroid Hormone	Rohit Sinha, MD and Paul M. Yen, MD
7. Physiology of the Hypothalamic-Pituitary Thyroid Axis	Stefano Mariotti, MD and Paolo Beck-Peccoz, MD
THYROID TESTING
8. Assay of Thyroid Hormones and Related Substances	Carole A. Spencer, PhD
9. Clinical Strategies in the Testing of Thyroid Function	Ulla Feldt-Rasmussen, MD, DMSc and Marianne Klose, MD, DMSc
10. Ultrasonography of the Thyroid	Manfred Blum, MD
11. Fine-Needle Aspiration of the Thyroid Gland	Sina Jasim, MD, MPH, Diana S. Dean, MD, FACE and Hossein Gharib, MD, MACP, MACE
12. Evaluation of Thyroid Function in Health and Disease	Jayne Franklyn and Michael Shephard
HYPOTHYROIDISM AND HYPERTHYROIDISM
13. Autoimmunity to the Thyroid Gland	Anthony Weetman and Leslie J. De Groot, MD
14. Hashimoto’s Thyroiditis	Takashi Akamizu, MD, PhD and Nobuyuki Amino, MD
15. Adult Hypothyroidism	Wilmar M. Wiersinga, MD, PhD
16. Graves’ Disease and the Manifestations of Thyrotoxicosis	David Toro-Tobon, MD and Marius N. Stan, MD
17. Diagnosis and Treatment of Graves’ Disease	Leslie J. De Groot, MD
18. Graves’ Disease: Complications	Luigi Bartalena, MD
19. Thyrotoxicosis of other Etiologies	Peter Kopp, MD
20. Thyrotropin-Secreting Pituitary Adenomas	Paolo Beck-Peccoz, MD, Luca Persani, MD, PhD and Andrea Lania, MD, PhD
DISORDERS OF PREGNANCY AND CHILDHOOD
21. Thyroid Regulation and Dysfunction in the Pregnant Patient	John Lazarus, MA, MD, FRCP, FRCOG, FACE
22. Thyroid Nodules and Thyroid Cancer Prior to, During, and Following Pregnancy	Christopher W. Rowe and Kristien Boelaert
23. Thyroid Hormones in Brain Development and Function	Juan Bernal, MD
24. Disorders of the Thyroid Gland in Infancy, Childhood and Adolescence	Maria Segni, MD
GENETIC DISORDERS
25. TSH Receptor Mutations and Diseases	Gunnar Kleinau, MD and Gilbert Vassart, MD
26. Genetic Defects in Thyroid Hormone Supply	Immacolata Cristina Nettore, Gianfranco Fenzi, MD and Paolo E. Macchia, MD, PhD
27. Defects of Thyroid Hormone Transport in Serum	Samuel Refetoff, MD
28. Impaired Sensitivity to Thyroid Hormone: Defects of Transport, Metabolism and Action	Alexandra M. Dumitrescu, Manassawee Korwutthikulrangsri and Samuel Refetoff, MD
NODULES AND CANCER
29. Multinodular Goiter	Geraldo Medeiros-Neto, MD
30. Thyroid Nodules	Furio Pacini, MD and Leslie J. De Groot, MD
31. Thermal Ablation for Thyroid Nodules	Jung Hwan Baek, MD, PhD and So Yeong Jeong, MD, PhD
32. Thyroid Cancer	Furio Pacini, MD and Leslie J. De Groot, MD
33. Surgery of the Thyroid	Edwin Kaplan, MD, Peter Angelos, MD, PhD, Megan Applewhite, MD, Frederic Mercier, MD and Raymon Grogan, MD
THYROID DISEASE IN OLDER ADULTS
34. Hyperthyroidism in Aging	Mary H. Samuels, MD
35. Hypothyroidism in Older Adults	Matthew I. Kim, MD
36. Thyroid Nodules and Cancer in the Elderly	Melissa G. Lechner, MD, PhD and Jerome Hershman, MD
MISCELLANEOUS
37. Effects of the Environment, Chemicals and Drugs on Thyroid Function	David Sarne, MD
38. The Non-Thyroidal Illness Syndrome	Leslie J. De Groot, MD
39. Acute and Subacute, and Riedel’s Thyroiditis	Priyanka Majety, MD and James V. Hennessey, MD, FACP
40. The Iodine Deficiency Disorders	Creswell J. Eastman, MD and Michael B. Zimmermann, MD

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