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Long-term TSH suppression in Graves- hyperthyroidism

Topic: GRAVES- HYPERTHYROIDISM Title: Continued suppression of serum TSH level may be attributed to TSH receptor antibody activity as well as the severity of thyrotoxicosis and the time to recovery of thyroid hormone in treated euthyroid Graves- patients. Authors: Chung YJ, Lee BW, Kim J-Y, Jung JH, Min Y-K, Lee M-S, Lee M-K, Kim K-W, […]

Iodine Supplements in Hashimoto’s Thyroiditis

Question Patients with Hashimoto’s thyroiditis are more susceptible to developing a Wolf-Chaikoff reaction to iodine excess than patients without thyroid disease. Yet pregnant women are all being recommended by some to take 250 mcg of iodine during pregnancy and lactation. If you make sure pre-pregancy hypothyroid patients are treated to assure TSH<2,5 and once pregnant […]

Neonate with Possible Hypothyroidism

Question 2 month old baby,male, was born full term, birth weight 3.2kg. No neonatal complications. No hipoglicemia, jaundice or micropenis. Normal newborn screening (Normal TSH and Free T4). Maternal data: no medications during pregnancy or breastfeeding, no problems during pregnancy. Normal Thyroid function test.No hoarse cry, facial puffiness, umbilical hernia, hypotonia, mottling, cold hands and […]

Normal Thyroid Tests Except for Elevated RT3

Question I am a physician who practice in El Paso, TX. I just got a patient complaining of fatigue with the following thyroid panel results: TSH – 2.04 uIU/mL T4 Total – 8.55 ug/dL (4.87 – 11.72) T Uptake – 43.3 % (32 – 51) Free Tiroxine Index – 9.26 ug/dL (5.93 – 13.13) T3 […]

Neonate with Large Goiter

Question Full term newborn male with a hx of IUGR in utero born to a mother who smoked during pregnancy but who has no hx of thyroid problems, who at birth has some respiratory distress and is noted to have a large neck mass. TSH is 775mcIU/ml and free T4 is 0.39 ng/dl so he […]

Evaluation of Thyroid Function in Health and Disease

Archived This chapter has been superceded by  newer chapters (See Homepage). However this Chapter, written originally by Dr Samuel Refetoff and updated by Drs Franklyn and Shephard, remains a treasure trove of information on many now-obscure thyroid tests, and references. For that reason we maintain it as a part of our Archive for use of […]