TOPIC: Thyroxine replacement therapy Title: Serum T3 levels in athyreotic individuals during thyroxine therapy. Authors: Jonklaas J, Davidson B, Bhagat S, & Soldin SJ. Reference: Journal of the American Medical Association 20: 769-777, 2008 Summary Background Some hypothyroid patients on thyroxine (LT4) therapy report a variety of symptoms including poor mood, lethargy, and cognitive impairment […]

TOPIC: Tg-Ab measurements for prediction of recurrence in thyroid cancer Title: The prevalence of transient change of serum thyroglobulin antibody levels is useful for prediction of clinical recurrence in thyroglobulin-negative patients with differentiated thyroid carcinoma Authors: Kim WG , Yoon JH, Kim WB , Kim TY , Kim EY , Kim JM , Ryu JS […]

TOPIC: Thyroid hormone receptor Title: Thyroid hormone receptor alpha1 acts as a potent suppressor of tumor invasiveness and metastasis. Authors: Martinez-Iglesias O, Garcia-Silva S, Tenbaum SP, Regadera J, Larcher F, Paramio JM, Vennstrom B, & Aranda A. Reference: Cancer Research 69: 501-509, 2009 Summary Background Loss of thyroid hormone receptors (TR) is a common feature […]

TOPIC: Treatment of hypothyroid patients Title: High frequency of – and factors associated with – thyroid hormone over-replacement and under-replacement in men & women aged 65 and over. Authors: Somwaru LL, Arnold AM, Joshi N, Fried LP, & Cappola AR. Reference: Journal of Clinical Endocrinology & Metabolism (epub – ahead of print) January 6, 2009 […]

TOPIC: Thyroid autoimmunity in schoolchildren Title: Thyroid autoimmunity in schoolchildren in a long-standing iodine sufficient area: correlation with gender, pubertal stage and maternal autoimmunity. Authors: Kaloumenou I, Mastorakos G, Alevizaki M, Duntas LH, Mantzou E, Ladopoulos C, Antoniou A, Chiotis D, Papassotiriou I, Chrousos GP, & Dacou-Voutetakis C. Reference: Thyroid 18: 747-754, 2008 Summary Background […]