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Archives for November, 2007

Mild hypo-/hyperthyroidism & mortality in cardiac patients

TOPIC:Subclinical hypo- and hyperthyroidism and mortality Title: Association between increased mortality and mild thyroid dysfunction in cardiac patients. Authors: Ievarsie G, Molinaro S, Landi P, Taddei MC, Galli E, Mariani F, L-Abbate A, & Pingitore A. Reference: Archives of Internal Medicine 167: 1526-1532, 2007 Summary Background The clinical relevance of subclinical hypothyroidism (SCH) and subclinical […]

Iron deficiency and maternal thyroid function

TOPIC: Potential role of iron deficiency adversely affecting maternal thyroid function. Title: Iron deficiency predicts poor maternal thyroid status during pregnancy. Authors: Zimmerman MB, Burgi H, & Hurrell RF. Reference: Journal of Clinical Endocrinology & Metabolism 92: 3436-3440, 2007 Summary Background Pregnant women are often iron deficient during the 2 nd and 3 rd trimesters […]

Targeting thyroid hormone receptors with TH analogs

TOPIC: A novel thyroid hormone analog with potential clinical use Title: Single-dose targeting of thyroid hormone receptor- agonists to the liver reduces cholesterol and triglycerides and improves the therapeutic index. Authors: Erion MD, Cable EE, Ito BR, Jiang H, Fujitaki JM, Finn PD, Zhang B-H, Hou J, Boyer SH, van Poelje PD, & Linemeyer DL. […]

A TSHR mutation causing an imbalance between iodide trapping and organification

TOPIC: A new type of mutation in the TSH receptor Title: A familial thyrotropin (TSH) receptor mutation provides in vivo evidence that the inositol phosphates/Ca 2+ cascade mediates TSH action on thyroid hormone synthesis. Authors: Grasberger H , Van Sande J , Hag-Dahood MA , Tenenbaum-Rakover Y , & Refetoff S. Reference: Journal of Clinical […]

Thyroid & Pregnancy

TOPIC: Knowledge concerning thyroid diseases and pregnancy Title: Thyroid disease and pregnancy: degrees of knowledge. Authors: Rinaldi MD & Stagnaro-Green AS. Reference: Thyroid 17: 747-753, 2007 Summary Objective The literature on the impact of thyroid abnormalities on pregnancy and the postpartum has expanded rapidly over the last two decades. Objective of present study was to […]