TOPIC: Thyroid development Title: Early developmental specification of the thyroid gland depends on han-expressing surrounding tissue and on FGF signals. Authors: : Wendl T, Adzic D, Schoenebeck JJ, Scholpp S, Brand M, Yelon D, & Rohr KB. Reference: Development 134: 2871-2879, 2007 (doi:10.1242/dev.02872) Summary Background In all vertebrates, the thyroid gland develops from the ventral […]
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First identification of a mutation in the DUOXA2 gene, in a Chinese patient with CH due to a partial iodine organification defect
TOPIC: D yshormonogenesis due to mutations in DUOXA2 gene Title: Biallelic inactivation of the dual oxidase maturation factor 2 ( DUOXA2 ) gene as a novel cause of congenital hypothyroidism. Authors: Zamproni I, Grasberger H, Cortinovis F, Vigone MC, Chiumello G, Mora S, Onigata K, Fugazzola L, Refetoff S, Persani L, & Weber G. Reference: […]
Read more »Novel somatostatin analogs for treatment of Graves’ orbitopathy
TOPIC: Graves' orbitopathy Title: Modulation of expression of somatostatin receptor subtypes in Graves' ophthalmopathy orbits: relevance to novel analogues Authors: Cozma I, Zhang L, Uddin J, Lane C, Rees A, & Ludgate M Reference: Am J Physiol Endocrinol Metab 293: E1630-E1635, 2007 (ahead of print) Summary Background Treatment of Graves'orbitopathy (GO) with two somatostatin analogs, […]
Read more »Thyroid volume and echostructure in children
TOPIC: Factors influencing thyroid volume in school-age children in an area with iodine sufficiency Title: Thyroid volume and echo-structure in school children living in an iodine-replete area: relation to age, pubertal stage, and body mass index. Authors: Kaloumenou I, Alevizaki M, Ladopoulos C, Antoniou A, Duntas LH, Mastorakos G, Chiotis D, Mengreli C, Livadas S, […]
Read more »Is thyroxine administration the answer?
TOPIC: Autoimmune thyroid disease during pregnancy Title: Levothyroxine treatment in euthyroid pregnant women with autoimmune thyroid disease: effects on obstetrical complications. Authors: Negro R , Formoso G , Mangieri T , Pezzarossa A , Dazzi D , & Hassan H. Reference: Journal of Clinical Endocrinology & Metabolism 91:2587-2591, 2007 Summary Background Euthyroid women with autoimmune […]
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