Topic: Regulation of Expression of Na + /I – Symporter Title: PTTG and PBF repress the human sodium iodide symporter. Authors: Boelaert K, Smith VE, Stratford AL, Kogai T, Tannahill LA, Watkinson JC, Eggo MC, Franklyn JA, & McCabe CJ. Reference: Oncogene (advance online publication; 5 February 2007); doi: 10.1038/sj.onc.1210221 Summary Background The ability of […]

Topic: RhTSH & CONGENITAL HYPOTHYROIDISM Title: Recombinant thyrotropin in the diagnosis of congenital hypothyroidism. Authors: Tiosano D, Even L, Orr ZS, & Hochberg Z Reference: Journal of Clinical Endocrinology & Metabolism, 92: 1424-1437, 2007 Summary Background A modern approach to congenital hypothyroidism requires a definitive diagnosis of the underlying mechanisms; this can be achieved within […]

Topic: DOPPLER ULTRASONOGRAPHY & HYPERTHYROIDISM Title: Color Flow Doppler Sonography for the Etiologic Diagnosis of Hyperthyroidism. Authors: Erdogan MF, Anil C, Cesur M, Baskal N, and Erdogan G. Reference: Thyroid 17: 223-228, 2007 Summary Background Color flow Doppler sonography is gaining importance for the functional evaluation of thyroid disorders. Purpose The objective of this study […]

Topic: MECHANISM OF TSH RECEPTOR ACTIVATION Title: Suppression of thyrotropin receptor constitutive activity by a monoclonal antibody with inverse agonist activity. Authors: Chen C-R, McLachlan SM, & Rapoport B. Reference: Endocrinology, 2007 (First published ahead of print on February 1, 2007 as doi:10.1210/en.2006-1754) Summary Background Thyrotropin (TSH) binding to the TSH receptor (TSHR) induces thyrocyte […]

Topic: NON-THYROIDAL ILLNESS SYNDROME Title: Frequency and outcome of patients with non-thyroidal illness syndrome in a medical intensive care unit Authors: Plikat K , Langgartner J , Buettner R , Bollheimer LC , Woenckhaus U , Scholmerich J , Wrede CE. Reference: Metabolism 56: 239-244, 2007 Summary Background Acute and chronic critical conditions are associated […]