TOPIC: A novel thyroid hormone analog with potential clinical use Title: Single-dose targeting of thyroid hormone receptor- agonists to the liver reduces cholesterol and triglycerides and improves the therapeutic index. Authors: Erion MD, Cable EE, Ito BR, Jiang H, Fujitaki JM, Finn PD, Zhang B-H, Hou J, Boyer SH, van Poelje PD, & Linemeyer DL. […]
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A TSHR mutation causing an imbalance between iodide trapping and organification
TOPIC: A new type of mutation in the TSH receptor Title: A familial thyrotropin (TSH) receptor mutation provides in vivo evidence that the inositol phosphates/Ca 2+ cascade mediates TSH action on thyroid hormone synthesis. Authors: Grasberger H , Van Sande J , Hag-Dahood MA , Tenenbaum-Rakover Y , & Refetoff S. Reference: Journal of Clinical […]
Read more »Thyroid & Pregnancy
TOPIC: Knowledge concerning thyroid diseases and pregnancy Title: Thyroid disease and pregnancy: degrees of knowledge. Authors: Rinaldi MD & Stagnaro-Green AS. Reference: Thyroid 17: 747-753, 2007 Summary Objective The literature on the impact of thyroid abnormalities on pregnancy and the postpartum has expanded rapidly over the last two decades. Objective of present study was to […]
Read more »TSH receptor antibodies: risk of recurrence and orbitopathy
TOPIC: Graves-orbitopathy Title: Patients with severe Graves- ophthalmopathy have a higher risk of relapsing hyperthyroidism and are unlikely to remain in remission. Authors: Ecktsein AK, Lax H, Losch C, Glowacka D, Plicht M, Mann K, Esser J & Morgenthaler NG. Reference: Clinical Endocrinology 67: 607-612, 2007 Summary Background Graves- hyperthyroidism and orbitopathy (GO) are frequently […]
Read more »FNA in medullary thyroid carcinoma
TOPIC: Hormone determinations in wash-out fluid from FNA Title: Calcitonin measurement in wash-out fluid from fine needle aspiration of neck masses in patients with primary and metastatic medullary thyroid carcinoma. Authors: Boi F, Maurelli I, Pinna G, Atzeni F, Piga M, Lai ML, & Mariotti S. Reference: Journal of Clinical Endocrinology & Metabolism 92: 2115-2118, […]
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