Thyroid cancer recurrence in patients clinically free of disease with undetectable or very low serum thyroglobulin values. Kloos RT J Clin Endocrinol Metab. 2010 Dec;95(12):5241-8. Epub One hundred seven patients had initial thyroid cancer surgery and subsequent remnant radioiodine ablation. Patients underwent recombinant human TSH (rhTSH)-mediated diagnostic whole-body scan and rhTSH-stimulated thyroglobulin (Tg) measurement before […]
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An Extensive Review of the Role of Selenium in Thyroid Homeostasis
Selenium and the thyroid: a close-knit connection. Duntas LH J Clin Endocrinol Metab. 2010 Dec;95(12):5180-8. Epub 2010 Sep 1. The recent recognition that the essential trace element selenium is incorporated as selenocysteine in all three deiodinases has decisively confirmed the clear-cut link between selenium and thyroid function. It has additionally been established that the thyroid […]
Read more »Making the Case for RAI Treatment of Intra-thoracic Goiter
Approach to management of the patient with primary or secondary intrathoracic goiter. Hegedüs L , Bonnema SJ J Clin Endocrinol Metab. 2010 Dec;95(12):5155-62. Intrathoracic (substernal) goiter, depending on definition, is seen in up to 45% of all patients operated for goiter. It can either be primary (ectopic thyroid tissue detached from a cervical thyroid mass), […]
Read more »Correlation of BRAF V600E mutations and tumor invaseness in papillary thyroid carcinoma
JCEM 2010, 95(9):4197-4205 Basolo et al Evaluation of the degree of neoplastic infiltration beyond the thyroid capsule remains a unique parameter that can be evaluated by histopathological examination to label a papillary thyroid carcinoma (PTC) of 20 mm or less in size as a pT1 or pT3 tumor. We correlated the BRAF V600E mutation with […]
Read more »High efficacy of concomitant treatment of undifferentiated (anaplastic) thyroid cancer with radiation and docetaxel
J Clin Endocrinol Metab. 2010 Sep;95(9):E54-7. Epub 2010 Jun 30. Troch M , Koperek O , Scheuba C , Dieckmann K , Hoffmann M , Niederle B , Raderer M Anaplastic thyroid carcinoma (ATC) is a rare but aggressive solid tumor with a very short survival time even with multimodality treatment. In view of in […]
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