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Archives for October, 2014

Current Treatment Modalities for Spinal Metastases Secondary to Thyroid Carcinoma.

Kushchayeva YS1, Kushchayev SV, Wexler JA, Carroll NM, Preul MC, Teytelboym OM, Sonntag VK, Van Nostrand D, Burman KD, Boyle LM. Thyroid. 2014 Oct;24(10):1443-1455 The spine is the most common site of bone metastases due to thyroid cancer, which develop in more than 3% of patients with well-differentiated thyroid cancer. Nearly half of patients with […]

The Attitude Toward Hypothyroidism During Early Gestation: Time for a Change of Mind?

Pop V1, Broeren M, Wiersinga W. Thyroid. 2014 Oct;24(10):1541-1546. The approach not to screen thyroid function of all pregnant women is mainly based on conflicting evidence of whether treatment of women with mild hypothyroidism is beneficial. However, there is consensus that all women with overt hypothyroidism (OH) and those with a thyrotropin (TSH) >10 mIU/L […]

Non-Thyroidal Illness in the ICU: A Syndrome with Different Faces.

Van den Berghe G. Thyroid. 2014 Oct;24(10):1456-1465 PMID: 24845024 Critically ill patients typically present with low or low-normal plasma thyroxine, low plasma triiodothyronine (T3), increased plasma reverse T3 (rT3) concentrations, in the absence of a rise in thyrotropin (TSH). This constellation is referred to as nonthyroidal illness syndrome (NTI). Although it is long known that […]

Smoking Induces Overexpression of Immediate Early Genes in Active Graves’ Ophthalmopathy

Planck T1, Shahida B, Parikh H, Ström K, Asman P, Brorson H, Hallengren B, Lantz M. Thyroid. 2014 Oct;24(10):1524-1532.. PMID: 25135760 Cigarette smoking is a risk factor for the development of Graves’ ophthalmopathy (GO). In a previous study of gene expression in intraorbital fat, adipocyte-related immediate early genes (IEGs) were overexpressed in patients with GO […]

Hypothyroidism is a predictor of disability pension and loss of labor market income:

Hypothyroidism is a predictor of disability pension and loss of labor market income: a danish register-based study. Thvilum M1, Brandt F, Brix TH, Hegedüs L. J Clin Endocrinol Metab. 2014 Sep;99(9):3129-35 Hypothyroidism is associated with an increased somatic and psychiatric disease burden..We compared with a matched control group, the risk of receiving disability pension (before […]