TOPIC: TSH reference range increases with aging Title: Extreme longevity is associated with increased serum thyrotropin. Authors: Atzmon G, Barzilai N, Hollowell JG, Surks MI, & Gabriely I. Reference: Journal of Clinical Endocrinology & Metabolism 94: 1251-1254, 2009 Summary Context The TSH reference range, specifically the setting of the upper reference limit, is currently controversial. […]

TOPIC: Prognostic value of early postoperative serum Tg measured without TSH stimulation in DTC Title: Thyroglobulin measurement before rhTSH-aided 131 I ablation in detecting metastases from differentiated thyroid carcinoma. Authors: Giovanella L, Ceriani L, Suriano S, Ghelfo A, & Maffioli M. Reference: Clinical Endocrinology 69, 659–663, 2008 Summary Context The practice of routinely treating DTC […]

TOPIC: Free T4 measurements during pregnancy Title: Tandem mass spectrometry improves the accuracy of free T4 measurements during pregnancy. Authors: Kahric-Janicic N, Soldin SJ, Soldin OP, West T, Gu J, & Jonklaas J. Reference: Thyroid 17: 303-311, 2007 Summary Objective The aim of the study was to compare a new tandem mass spectrometric (LC/MS/MS) method […]

Topic: Sensitive Tg assays and recombinant human TSH (rhTSH) Title: Monitoring thyroglobulin in a sensitive immunoassay has comparable sensitivity to recombinant human TSH-stimulated thyroglobulin in the follow-up of thyroid cancer patients. Authors: Smallridge RC , Meek SE , Morgan MA , Gates GS , Fox TP , Grebe S , & Fatourechi V Reference: Journal […]