* Second of a new series of ‘Mini-Editorials’ in ‘Thyroid News’ While accounting for only 1% of solid malignancies, thyroid carcinoma is the most common malignancy of the endocrine system. The majority are patients with well-differentiated thyroid carcinoma of follicular cell origin who are cured with adequate surgical management and radioiodine therapy. However, some thyroid […]

TOPIC: Use and misuse of thyroid cancer cell lines Title: DNA profiling analysis of 40 human thyroid cancer cell lines reveals cross-contamination resulting in cell line redundancy and mis-identification. Authors: Schweppe RE, Kloppe JP, Korch C, Pugazhenthi U, Benezra M, Knauf JA, Fagin JA, Marlow L, Copland JA, Smallridge RC, & Haugen BR. Reference: Journal […]

TOPIC: Methodological issues with serum thyroglobulin measurements Title: Comparison of seven serum thyroglobulin assays in the follow-up of papillary and follicular thyroid cancer patients Authors: Schlumberger M, Hitzel A, Toubert ME, Corone C, et al. Reference: Journal of Clinical Endocrinology & Metabolism 92:2487-2495, 2007 Summary Objectives Serum thyroglobulin (Tg) is the most sensitive and specific […]

Topic: THYROID CANCER Title: Trend in thyroid carcinoma size, age at diagnosis, and histology in a retrospective study of 500 cases diagnosed over 20 years. Authors: Trimboli P, Graziano FM, Marzullo A, Ruggieri M, Calvanese A, Piccirilli F, Cavaliere R, Fumarola A, D-Armiento M. Reference: Thyroid 16: 1151-1155, 2006 Summary Background Recently, several reports have […]