TOPIC: Treatment of transient hypothyroxinemia of prematurity Title: Phase 1 trial of four thyroid hormone regimens for transient hypothyroxinemia in neonates of less than 28 weeks’ gestation . Authors: La Gamma EF, van Wassenaer AG, Ares S, Golumbek SG, Kok JH, Quero J, Hong T, Rahbar MH, Morreale de Escobar G, Fisher DA, & Paneth […]

TOPIC: TSH receptor Title: Small-molecule agonists for the thyrotropin receptor stimulate thyroid function in human thyrocytes and mice. Authors: Neumann S, Huang W, Titus S, Krause G, Kleinau G, Alberobello AT, Zheng W, Southall NT, Inglese J, Austin CP, Celi FS, Gavrilova O, Thomas CT, Raaka BM, & Gershengorn MC . Reference: Proc. Natl. Acad. […]

TOPIC: A biologically inactive TRH due to a mutant TRH-receptor Title: A family with complete resistance to thyrotropin-releasing hormone Authors: Bonomi M, Busnelli M, Beck-Peccoz P, Constanzo D, Antonica F, & Dolci C. Reference: New England Journal of Medicine 360: 731-734, 2009 Summary Background Recessive resistance to the action of TRH is a rare disorder […]

TOPIC: The importance of pre-ablation RAI scans Title: The utility of radioiodine scans prior to I131 ablation in patients with well-differentiated thyroid cancer Authors: Van Nostrand D, Aiken M, Atkins F, Moreau S, Garcia C, Acio E, Burman K, & Wartofsky L. Reference: Thyroid 2009 March 13 [Epub ahead of print] Summary Background The utility […]

* Second of a new series of ‘Mini-Editorials’ in ‘Thyroid News’ While accounting for only 1% of solid malignancies, thyroid carcinoma is the most common malignancy of the endocrine system. The majority are patients with well-differentiated thyroid carcinoma of follicular cell origin who are cured with adequate surgical management and radioiodine therapy. However, some thyroid […]