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Author Profile

Samuel Refetoff, M.D.

Departments of Medicine and Pediatrics, Committees on Genetics and Molecular Medicine and the J.P. Kennedy Jr. Mental Retardation Research Center, The University of Chicago, Chicago, Illinois 60637-1470

Recent Posts

Thyroid hormone transport into the brain

TOPIC: Role of membrane transporters of thyroid hormone on their transfer into the brain Title: Expression of the thyroid hormone transporter MCT8 (SLC16A2) and AOTP14 (SLC01C1) at the blood-brain barrier. Authors: Roberts LM, Woodford K, Zhou M, Black DS, et al. Reference: Endocrinology 149: 6251-6261, 2008 Summary Background Thyroid hormones require transport across cell membranes […]

Local expression of TR’2 & cone photoreceptor differentiation

TOPIC: Patterning of retinal cone photoreceptor development Title: NeuroD1 regulates expression of thyroid hormone receptor '2 and cone opsins in the developing mouse retina. Authors: Liu H, Etter P, Hayes S, Jones I, Nelson B, Hartman B, Forrest D, & Reh T. Reference: The Journal of Neuroscience, 28: 749-756, 2008 Summary Objective The correct patterning […]

Congenital hypothyroidism: an experience of nature in mice

Topic: Mutations in congenital hypothyroidism Title -Congenital hypothyroidism, dwarfism and hearing impairment caused by a missense mutation in the mouse dual oxidase 2 gene, Duox 2. Authors: Johnson KR, Marden CC, Ward-Bailey P, Gagnon LH, Bronson RT, & Donahue LR Reference: Molecular Endocrinology (first published ahead of print April 17, 2007) Summary Background The mouse […]