Vadiveloo T , Donnan PT , Cochrane L , Leese GP The Thyroid Epidemiology, Audit, and Research Study (TEARS): the natural history of endogenous subclinical hyperthyroidism. J Clin Endocrinol Metab. 2011 Jan;96(1):E1-8. Epub 2010 Oct 6. This study was to define the rates of progression from subclinical hyperthyroidism (SH) to frank hyperthyroidism and normal thyroid […]
Category archives for Uncategorized
Levels of neonatal thyroid hormone in preterm infants and neurodevelopmental outcome at 5 1/2 years: millennium cohort study. Delahunty C , Falconer S , Hume R , Jackson L , Midgley P , Mirfield M , Ogston S , Perra O , Simpson J , Watson J , Willatts P , Williams F ; Scottish […]
Papillary Thyroid Cancer Study Group . Durante C , Attard M , Torlontano M , Ronga G , Monzani F , Costante G , Ferdeghini M , Tumino S , Meringolo D , Bruno R , De Toma G , Crocetti U , Montesano T , Dardano A , Lamartina L , Maniglia A , […]
Prophylactic central neck dissection and local recurrence in papillary thyroid cancer: a meta-analysis. Zetoune T , Keutgen X , Buitrago D , Aldailami H , Shao H , Mazumdar M , Fahey TJ 3rd , Zarnegar R Ann Surg Oncol. 2010 Dec;17(12):3287-93. The effectiveness of prophylactic central neck dissection (pCND) in the treatment of patients […]
Real-time elastosonography: useful tool for refining the presurgical diagnosis in thyroid nodules with indeterminate or nondiagnostic cytology. Rago T , Scutari M , Santini F , Loiacono V , Piaggi P , Di Coscio G , Basolo F , Berti P , Pinchera A , Vitti P . J Clin Endocrinol Metab. 2010 Dec;95(12):5274-80. Epub […]
Thyroid cancer recurrence in patients clinically free of disease with undetectable or very low serum thyroglobulin values. Kloos RT J Clin Endocrinol Metab. 2010 Dec;95(12):5241-8. Epub One hundred seven patients had initial thyroid cancer surgery and subsequent remnant radioiodine ablation. Patients underwent recombinant human TSH (rhTSH)-mediated diagnostic whole-body scan and rhTSH-stimulated thyroglobulin (Tg) measurement before […]
Selenium and the thyroid: a close-knit connection. Duntas LH J Clin Endocrinol Metab. 2010 Dec;95(12):5180-8. Epub 2010 Sep 1. The recent recognition that the essential trace element selenium is incorporated as selenocysteine in all three deiodinases has decisively confirmed the clear-cut link between selenium and thyroid function. It has additionally been established that the thyroid […]
Approach to management of the patient with primary or secondary intrathoracic goiter. Hegedüs L , Bonnema SJ J Clin Endocrinol Metab. 2010 Dec;95(12):5155-62. Intrathoracic (substernal) goiter, depending on definition, is seen in up to 45% of all patients operated for goiter. It can either be primary (ectopic thyroid tissue detached from a cervical thyroid mass), […]
J Clin Endocrinol Metab. 2010 Sep;95(9):E54-7. Epub 2010 Jun 30. Troch M , Koperek O , Scheuba C , Dieckmann K , Hoffmann M , Niederle B , Raderer M Anaplastic thyroid carcinoma (ATC) is a rare but aggressive solid tumor with a very short survival time even with multimodality treatment. In view of in […]
JCEM 2010, 95(9):4197-4205 Basolo et al Evaluation of the degree of neoplastic infiltration beyond the thyroid capsule remains a unique parameter that can be evaluated by histopathological examination to label a papillary thyroid carcinoma (PTC) of 20 mm or less in size as a pT1 or pT3 tumor. We correlated the BRAF V600E mutation with […]
The Birmingham Elderly Thyroid study. Parle J , Roberts L , Wilson S , Pattison H , Roalfe A , Haque MS , Heath C , Sheppard M , Franklyn J , Hobbs FD J Clin Endocrinol Metab. 2010 Aug;95(8):3623-32. Epub 2010 May 25. Subclinical hypothyroidism (SCH) and cognitive dysfunction are both common in the […]
Subclinical hypothyroidism and the risk of coronary heart disease and mortality. Rodondi N , den Elzen WP , Bauer DC , Cappola AR , Razvi S , Walsh JP , Asvold BO , Iervasi G , Imaizumi M , Collet TH , Bremner A , Maisonneuve P , Sgarbi JA , Khaw KT , Vanderpump […]
Recombinant human thyrotropin-stimulated radioiodine therapy of nodular goiter allows major reduction of the radiation burden with retained efficacy. Fast S , Hegedüs L , Grupe P , Nielsen VE , Bluhme C , Bastholt L , Bonnema SJ J Clin Endocrinol Metab. 2010 Aug;95(8):3719-25. Epub 2010 Jun 2. Stimulation with recombinant human TSH (rhTSH) before […]
Iodine biokinetics and radioiodine exposure after recombinant human thyrotropin-assisted remnant ablation in comparison with thyroid hormone withdrawal. Taieb D , Sebag F , Farman-Ara B , Portal T , Baumstarck-Barrau K , Fortanier C , Bourrelly M , Mancini J , De Micco C , Auquier P , Conte-Devolx B , Henry JF , Mundler […]
Treatment with tyrosine kinase inhibitors for patients with differentiated thyroid cancer: the M. D. Anderson experience. Cabanillas ME , Waguespack SG , Bronstein Y , Williams MD , Feng L , Hernandez M , Lopez A , Sherman SI , Busaidy NL J Clin Endocrinol Metab. 2010 Jun;95(6):2588-95. Epub 2010 Apr 14. Cabanillas et al […]
TOPIC: Treatment of transient hypothyroxinemia of prematurity Title: Phase 1 trial of four thyroid hormone regimens for transient hypothyroxinemia in neonates of less than 28 weeks’ gestation . Authors: La Gamma EF, van Wassenaer AG, Ares S, Golumbek SG, Kok JH, Quero J, Hong T, Rahbar MH, Morreale de Escobar G, Fisher DA, & Paneth […]
TOPIC: TSH receptor Title: Small-molecule agonists for the thyrotropin receptor stimulate thyroid function in human thyrocytes and mice. Authors: Neumann S, Huang W, Titus S, Krause G, Kleinau G, Alberobello AT, Zheng W, Southall NT, Inglese J, Austin CP, Celi FS, Gavrilova O, Thomas CT, Raaka BM, & Gershengorn MC . Reference: Proc. Natl. Acad. […]
TOPIC: A biologically inactive TRH due to a mutant TRH-receptor Title: A family with complete resistance to thyrotropin-releasing hormone Authors: Bonomi M, Busnelli M, Beck-Peccoz P, Constanzo D, Antonica F, & Dolci C. Reference: New England Journal of Medicine 360: 731-734, 2009 Summary Background Recessive resistance to the action of TRH is a rare disorder […]
TOPIC: The importance of pre-ablation RAI scans Title: The utility of radioiodine scans prior to I131 ablation in patients with well-differentiated thyroid cancer Authors: Van Nostrand D, Aiken M, Atkins F, Moreau S, Garcia C, Acio E, Burman K, & Wartofsky L. Reference: Thyroid 2009 March 13 [Epub ahead of print] Summary Background The utility […]
* Second of a new series of ‘Mini-Editorials’ in ‘Thyroid News’ While accounting for only 1% of solid malignancies, thyroid carcinoma is the most common malignancy of the endocrine system. The majority are patients with well-differentiated thyroid carcinoma of follicular cell origin who are cured with adequate surgical management and radioiodine therapy. However, some thyroid […]
TOPIC: A role for Th17 T cells in AITD Title: Increases of the Th1/Th2 cell ratio in severe Hashimoto’s disease and in the proportion of Th17 cells in intractable Graves’ disease. Authors: Nanba T , Watanabe M , Inoue N , & Iwatani Y . Reference: Thyroid 19: 495-501, 2009 Summary Background CD4+ T cells […]
TOPIC: Incidence of thyroid cancer in France (1998-2006) Title: Thyroid cancer: is the incidence rise abating? Authors: Sassolas G, Hafdi-Nejjari Z, Remontet L, Bossard N, Belot A, Berger-Dutrieux N, Decaussin-Petrucci M, Bournaud C, Peix zithromax online JL, Orgiazzi J, Borson-Chazot F, and the ‘Group of Pathologists’ of the Rhône-Alpes Region. Reference: European Journal of Endocrinology […]
TOPIC: TSH reference range increases with aging Title: Extreme longevity is associated with increased serum thyrotropin. Authors: Atzmon G, Barzilai N, Hollowell JG, Surks MI, & Gabriely I. Reference: Journal of Clinical Endocrinology & Metabolism 94: 1251-1254, 2009 Summary Context The TSH reference range, specifically the setting of the upper reference limit, is currently controversial. […]
TOPIC: S onographic appearance of cystic thyroid nodules Title: Partially cystic thyroid nodules on ultrasound: probability of malignancy and sonographic differentiation. Authors: Lee M-J, Kim E-K, Kwak JY, & Kim MJ. Reference: Thyroid 19: 341-346, 2009 Summary Background Thyroid nodules are very common and a large portion of them are mixed echoic, with both solid […]
TOPIC: Thyroid function in pregnancy Title: Cigarette smoking during pregnancy is associated with alterations in maternal and fetal thyroid function. Authors: Shields B, Hill A, Bilous M, Knight B, Hattersley AT, Bilous RW, & Vaidya B. Reference: Journal of Clinical Endocrinology & Metabolism 94: 570-574, 2009 Summary Background Studies in the general population have shown […]