Topic: Mutations in congenital hypothyroidism Title -Congenital hypothyroidism, dwarfism and hearing impairment caused by a missense mutation in the mouse dual oxidase 2 gene, Duox 2. Authors: Johnson KR, Marden CC, Ward-Bailey P, Gagnon LH, Bronson RT, & Donahue LR Reference: Molecular Endocrinology (first published ahead of print April 17, 2007) Summary Background The mouse […]

Topic: Sensitive Tg assays and recombinant human TSH (rhTSH) Title: Monitoring thyroglobulin in a sensitive immunoassay has comparable sensitivity to recombinant human TSH-stimulated thyroglobulin in the follow-up of thyroid cancer patients. Authors: Smallridge RC , Meek SE , Morgan MA , Gates GS , Fox TP , Grebe S , & Fatourechi V Reference: Journal […]

Topic: Regulation of Expression of Na + /I – Symporter Title: PTTG and PBF repress the human sodium iodide symporter. Authors: Boelaert K, Smith VE, Stratford AL, Kogai T, Tannahill LA, Watkinson JC, Eggo MC, Franklyn JA, & McCabe CJ. Reference: Oncogene (advance online publication; 5 February 2007); doi: 10.1038/sj.onc.1210221 Summary Background The ability of […]

Topic: RhTSH & CONGENITAL HYPOTHYROIDISM Title: Recombinant thyrotropin in the diagnosis of congenital hypothyroidism. Authors: Tiosano D, Even L, Orr ZS, & Hochberg Z Reference: Journal of Clinical Endocrinology & Metabolism, 92: 1424-1437, 2007 Summary Background A modern approach to congenital hypothyroidism requires a definitive diagnosis of the underlying mechanisms; this can be achieved within […]

Topic: DOPPLER ULTRASONOGRAPHY & HYPERTHYROIDISM Title: Color Flow Doppler Sonography for the Etiologic Diagnosis of Hyperthyroidism. Authors: Erdogan MF, Anil C, Cesur M, Baskal N, and Erdogan G. Reference: Thyroid 17: 223-228, 2007 Summary Background Color flow Doppler sonography is gaining importance for the functional evaluation of thyroid disorders. Purpose The objective of this study […]