TOPIC: Tg-Ab measurements for prediction of recurrence in thyroid cancer Title: The prevalence of transient change of serum thyroglobulin antibody levels is useful for prediction of clinical recurrence in thyroglobulin-negative patients with differentiated thyroid carcinoma Authors: Kim WG , Yoon JH, Kim WB , Kim TY , Kim EY , Kim JM , Ryu JS […]

TOPIC: Treatment of hypothyroid patients Title: High frequency of – and factors associated with – thyroid hormone over-replacement and under-replacement in men & women aged 65 and over. Authors: Somwaru LL, Arnold AM, Joshi N, Fried LP, & Cappola AR. Reference: Journal of Clinical Endocrinology & Metabolism (epub – ahead of print) January 6, 2009 […]

TOPIC: Thyroid hormone receptor Title: Thyroid hormone receptor alpha1 acts as a potent suppressor of tumor invasiveness and metastasis. Authors: Martinez-Iglesias O, Garcia-Silva S, Tenbaum SP, Regadera J, Larcher F, Paramio JM, Vennstrom B, & Aranda A. Reference: Cancer Research 69: 501-509, 2009 Summary Background Loss of thyroid hormone receptors (TR) is a common feature […]

TOPIC: Thyroid autoimmunity in schoolchildren Title: Thyroid autoimmunity in schoolchildren in a long-standing iodine sufficient area: correlation with gender, pubertal stage and maternal autoimmunity. Authors: Kaloumenou I, Mastorakos G, Alevizaki M, Duntas LH, Mantzou E, Ladopoulos C, Antoniou A, Chiotis D, Papassotiriou I, Chrousos GP, & Dacou-Voutetakis C. Reference: Thyroid 18: 747-754, 2008 Summary Background […]

TOPIC: Genes involved in early thyroid development Title: Expression of Islet1 in thyroid deve buy cheap kamagra lopment related to budding, migration, and fusion of primordia. Authors: Westerlund J, Andersson L, Carlsson T, Zoppoli P, Fagman H, & Nilsson M. Reference: Developmental Dynamics 237, 3820-3829, 2008 Summary Background The thyroid is populated by two endocrine […]

TOPIC: Thymus contribution to thyroid autoimmunity Title: Influx of recent thymic emigrants into autoimmune thyroid disease glands in humans. Authors: Armengol MP, Sabater L, Fernandez M, Ruiz M, Alonso M, Otero MJ, Martinez-Caceres E, Jaraquemada E, & Pujol-Borrell R. Reference: Clinical & Experimental Immunology 153: 338-350, 2008 Summary Background The aetiology of autoimmune thyroid disease […]

TOPIC: Hashimoto’s encephalopathy Title: Hashimoto's encephalopathy: epidemiology, pathogenesis and management Authors: Mocellin R , Walterfang M , & Velakoulis D . Reference: CNS Drugs 21: 799-811, 2007 Summary Background Hashimoto's encephalopathy is a term used to describe an encephalopathy of presumed autoimmune origin characterised by high titres of antithyroid peroxidase antibodies. In a similar fashion […]

TOPIC: Use and misuse of thyroid cancer cell lines Title: DNA profiling analysis of 40 human thyroid cancer cell lines reveals cross-contamination resulting in cell line redundancy and mis-identification. Authors: Schweppe RE, Kloppe JP, Korch C, Pugazhenthi U, Benezra M, Knauf JA, Fagin JA, Marlow L, Copland JA, Smallridge RC, & Haugen BR. Reference: Journal […]

TOPIC: Prognostic value of early postoperative serum Tg measured without TSH stimulation in DTC Title: Thyroglobulin measurement before rhTSH-aided 131 I ablation in detecting metastases from differentiated thyroid carcinoma. Authors: Giovanella L, Ceriani L, Suriano S, Ghelfo A, & Maffioli M. Reference: Clinical Endocrinology 69, 659–663, 2008 Summary Context The practice of routinely treating DTC […]

TOPIC: FNA in Subcentimeter Thyroid Nodules Title: The Value of Fine-Needle Aspiration Biopsy in Subcentimeter Thyroid Nodules Authors: Berker D, Aydin Y, Ustun I, Gul K, Tutuncu Y, Isik S, Delibasi T, Guler S. Reference: Thyroid 2008; 18:603-608 Summary Background The need to perform fine-needle aspiration biopsy (FNAB) on subcentimeter thyroid nodules is less clear […]

TOPIC: Percutaneous thyroid biopsy Title: Bilateral thyroid hematomas after fine-needle aspiration causing acute airway obstruction. Authors: Hor T & Lahiri SW. Reference: Thyroid 18: 567-570, 2008 Summary Background Percutaneous fine-needle biopsy (FNB) of thyroid nodules has been universally accepted as the most economical, dependable, and easy evaluation of thyroid nodules. FNB provides the best triage […]

TOPIC: Ultrasound of thyroid nodules Title: Benign and malignant thyroid nodules: US differentiation – A multicenter retrospective study. Authors: Moon WJ, Jung SL, Lee JH, Na DG, Baek JH, Lee YH, Kim J, Kim HS, Byun JS, Lee DH; & the Thyroid Study Group, the Korean Society of Neuro- and Head and Neck Radiology. Reference: […]

TOPIC: High prevalence of erectile dysfunction in untreated hyper- and hypothyroid patients Title: Erectile dysfunction in patients with hyper- and hypothyroidism: how common and should we treat? Authors: Krassas GE, Tziomalos K, Papadopoulou F, Pontikides N, & Perros P. Reference: Journal of Clinical Endocrinology & Metabolism 93: 1815-1819, 2008 Summary Background Erectile dysfunction (ED) is […]

TOPIC: Thyroid cancer Title: Inter-observer and intra-observer reproducibility in the histo-pathology of follicular thyroid carcinoma. Authors: Franc B, De La Salmoniere P, Lange F, Hoang C, Louvel A, De Roquancourt A, Vilde F, Hejblum G, Chevret S, & Chastang C. Reference: Human Pathology 34: 1092-1100, 2003 Summary Context Thyroid nodules are very common, and most […]

TOPIC: Vascular effects of TSH Title: Enhancement of vascular endothelial function by recombinant human thyrotrophin. Authors: Napoli R, Biondi B, Guardasole V, D'Anna C, De Sena A, Pirozzi C, Terracciano D, Mazzarella C, Matarazzo M, & Sacca L. Reference: Journal of Clinical Endocrinology & Metabolism 93: 1959-1963, 2008 Summary Background The cardiovascular consequences of thyroid […]

TOPIC: Calcitonin measurement for thyroid nodules: is it cost-effective? Title: Calcitonin measurement in the evaluation of thyroid nodules in the United States: A cost-effectiveness and decision analysis. Authors: Cheung K, Roman SA, Wang TS, Walker HD, & Sosa JA. Reference: Journal of Clinical Endocrinology & Metabolism 93: 2173-2180, 2008 Summary Background European studies have shown […]

TOPIC: Graves' orbitopathy Title: Methylprednisolone pulse therapy for patients with moderately severe Graves' orbitopathy: a prospective, randomized, placebo-controlled study. Authors: Van Geest RJ, Sasim IV, Koppenschaar HP, Kalmann R, Stravers SN, Bijlsma WR, & Mourits MP . Reference: European Journal of Endocrinology 158: 229-237, 2008 Summary Background Glucocorticoids, administered through different routes, are a mainstay […]

TOPIC: Relapse of hyperthyroidism in Graves' disease patients after discontinuation of antithyroid drug therapy Title: The prevalence of transient thyrotoxicosis after antithyroid drug therapy (ATD) in patients with Graves' disease. Authors: Kubota S, Takata K, Arishima T, Ohye H, et al. Reference: Thyroid 18 (1): 63-66, 2008 Summary Background When transient hyperthyroidism occurs after antithyroid […]

TOPIC: Iodine requirements & fortification in pregnancy Title: Iodine prophylaxis using iodized salt and risk of maternal thyroid failure in conditions of mild iodine deficiency. Authors: Moleti MC, Lo Presti VP, Campolo MC, Mattina F, Galletti M, Mandolfino M, Violi MA, Giorgianni G, De Domenico D, Trimarchi F, & Vermiglio F . Reference: Journal of […]

TOPIC: Thyroid nodules Title: Higher serum thyroid stimulating hormone level in thyroid nodule patients is associated with greater risks of differentiated thyroid cancer and avanced tumor stage. Authors: Haymart MR, Repplinger DJ, Leverson GE, Elson DF, Sippel RS, Jaume JC, & Chen H. Reference: Journal of Clinical Endocrinology & Metabolism 93: 809-814, 2008 Summary Context […]

TOPIC: Genetics of hypothalamic-pituitary axis Title: Heritability of serum TSH, free T4 and free T2 concentrations: a study of a large UK twin cohort. Authors: Panicker V, Wilson SG, Spector TD, Brown SJ, Falchi M, Richards JB, Surdulescu GL, Lim EM, Flectcher SJ, & Walsh JP. Reference: Clinical Endocrinology 68: 652-659, 2008 Summary Objective Thyroid […]

TOPIC: Dyshormonogenesis and congenital hypothyroidism Title: Mutations in the iodotyrosine deiodinase gene and hypothyroidism. Authors: Moreno JC, Klootwijk W, van Toor H, Pinto G, D'Alessandro M, L'ger A, Goudie D, Polak M, Gr'ters A, & Visser TJ. Reference: New England Journal of Medicine 358: 1811-1818, 2008 Summary Context DEHAL1 has been identified as the gene […]

TOPIC: Hashimoto's encephalopathy Title: Anti-thyroperoxidase antibodies from patients with Hashimoto's encephalopathy bind to cerebellar astrocytes. Authors: Blanchin S, Coffin C, Viader F, Ruf J, Carayon P et al. Reference: Journal of Neuroimmunology 192: 13-20, 2007 Summary Background Hashimoto's encephalopathy is a rare and controversial neurological disorder, which is responsive to treatment with corticosteroids and associated […]

TOPIC: P endrin gene mutation induces poor organification, iodine retention & high deiodinase activity Title: Pendred syndrome in two Galician Families: insights into clinical phenotypes through cellular, genetic and molecular studies. Authors: Palos F, Garcia-Rendueles ME, Araujo-Vilar D, Obregon MJ, Calvo RM et al. Reference: Journal of Clinical Endocrinology & Metabolism 93: 267-277, 2008 Summary […]

TOPIC: Congenital central hypothyroidism Title: Role of the Thyrotropin-Releasing Hormone stimulation test in diagnosis of congenital central hypothyroidism in infants. Authors: V an Tijn DA, de Vijlder JJM, & Vulsma T. Reference: Journal of Clinical Endocrinology & Metabolism 93: 410-419, 2008 Summary Context A shortage of thyroid hormone during prenatal life and the first years […]