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Any physician may submit a question regarding a thyroid patient to ldegroot@earthlink.net and one of our panel of expert thyroidologists will attempt to provide an answer as soon as possible by return Email. Physicians should provide adequate clinical information about the problem, and provide their name, office address, and telephone number. We will send an answer by Email to the address provided, and will publish the question and the response on this page. The name of the questioning physician WILL be published unless specific instruction not to do so is provided in the original Email. This service is available only to physicians.

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We attempt to answer important questions from readers, if time permits, and publish those of value to other readers in this column. Please send questions to Dr John Lazarus lazarus@cardiff.ac.uk

To read questions from patients click here.

ADEQUATE IODINE SUPPLEMENTATION IN INDIA??   22 July 2012

QUESTION-Currently, in India we are consuming iodized salts everyday still there is very high prevalence of thyroid cases. My question is that in clinical practice do doctors need to completely avoid any nutritional supplement containing iodine (100-150mcg), considering that we all are consuming iodine salts and additional iodine containing preparation though in nutritional amount will be harmful to patient. Kindly throw some light on this issue. Makwana Altaf A;  M.Pharmacy (Pharmacology)
RESPONSE-As you have correctly pointed out the Universal Salt Iodisation Program (USI) in India has had its “ups and downs” and there have been many reports in the literature of it not being as effective as one had hoped for.

Indeed, in a very recent publication in Clinical Endocrinology by Marwaha et al ( Vol 76,905-910) it is clear that iodine deficiency remains prominent in India. In the study population of schoolchildren in Delhi 16.4% had goitre  and 7.3% were hypothyroid.

If you cannot access the article please let me know and I will send it to you.

Dr Pandav from AAIMS informs me that current iodised salt coverage in India is only 71%, therefore one would expect to see persistence of endemic goitre and other manifestations of IDD.

The current WHO/ICCIDD/UNICEF recommendation is that where USI coverage is not effective then pregnant women should be taking an iodine supplement of 150 ug per day. There is no recommendation for men or children to take a supplement. It is recommended that iodine intake should not exceed 500 ug per day. The normal iodine  RDI for adults and children is 150 ug and for pregnant and breastfeeding women it should be 250 ug per day.
Sincerely, Prof C J Eastman AM

 

Questions from Doctors

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  4. Diffuse Lung Micro-mets with Residual Neck Nodes in Place
  5. Amiodarone Induced Thyrotoxicosis
  6. Prolonged TSH Suppression After Antithyroid Therapy of Graves
  7. Hypothyroidism and Ascites
  8. Oral T4 Causing a Rash?
  9. Lower Limit of TSH for Replacement T4 Treatment in Pregancy
  10. 131-I Treatment and Risk to Later Pregnancy
  11. Invasive Papillary Thyroid Cancer in a 71 Yr Old
  12. Graves’ Disease in Pregancy and Atd Allergy, Possible Treatment?
  13. Hyperthyroidism and Increasing LFT Abnormalities, What Therapy?
  14. Graves, Exophthalmos, Mediastinal Mass, Heart Disease?
  15. Need for Iodine Supplementation During Pregnancy
  16. Possible T4 Malabsorption and Abdominal Disease
  17. Possible Euthyroid Graves’ Disease
  18. Follicular Neoplasm in a 19yr Old Female
  19. Therapy of Probable (?) Sporadic MTC
  20. Iodine Deficiency and Hypothyroidism in Early Pregnancy
  21. Ovarian Mass and Hyperthyroidism
  22. Fna “Positive” Contralateral Node Following Hemithyroidectomy
  23. rhTSH vs Hormone Withdrawal in RAI Therapy
  24. Pet-scan Positive Mediastinal ? Met After RAI and Prior Nediastinal Operation
  25. Pregnant (Post RAI on T4) Woman with Elevated TSAb
  26. Repeated Miscarriages in a Young Woman with Hashimoto’s Thyroiditis and Antibodies
  27. Residual Papillary Cancer: RAI vs Surgery??
  28. Hurthle Cells in an FNA of a Hashimoto’s Gland
  29. Prior Radiation to Bone and Use of Teriparatide
  30. Treatment of 2.3cm Unifocal Follicular Variant of Papillary Cancer
  31. Possible Thyroid Hormone Resistance
  32. Intermittent Hyperthyroidism and Hypothyroidism
  33. Interferon Therapy and Hyperthyroidism
  34. RAI Ablation in Stage 1 Papillary Thyroid Cancer?
  35. Thyroid Cancer with High TG Response to TSH but Negative Scan
  36. Hot Nodule and Sub-clinical Hyperthyroidism
  37. Gestational Hypertyroidism?
  38. A Case of Galactorrhea
  39. RAI Treatment with Extensive Lung Metastases
  40. Therapy of Advance Follicular Thyroid Cancer
  41. Neonatal Goiter with Normal TFTs
  42. Multiple Drugs for Schizophrenia, and Low T4 and T3 Levels
  43. Tracheal Invasion in Papillary Thyroid Carcinoma
  44. Possible Effects of Amiodarone
  45. Treatment for Progressive Hurthle Cell Thyroid Carcinoma
  46. Primary Hypothyroidism and Worsening Exophthalmos
  47. Thyroid CA, Invasion, Positive Nodes, and TG Antibodies
  48. Radiation and Possible Thyroid Malignancy
  49. Thyroid Hormone Resistance Vs. TSH-oma
  50. Thyrotoxicosis with Low RAIU
  51. Hypergonadotropic Hypogonadism and Congenital Rubella
  52. Use PTU After MMI Induced LFT Abnormalities?
  53. Low T4 and T3 but Normal TSH
  54. Follow-up of an Incidentally Found Papillary CA
  55. Struma Ovarii with Malignancy
  56. Mild Hyperthyroidism, Questionable Cause
  57. Thyroiditis, Hypothyroidism, Pregnancy
  58. Papillary CA, AITD, Neg Ab, Pos TG
  59. Twin Pregnancy, Low TSH, Normal T4 and T3
  60. Hyperthyroidism, Low Uptake, Negative Ab
  61. Microcarcinoma in Teenager with Dyshormonogenesis
  62. Hot Nodule with Indeterminate Histology
  63. Management of a Mediastinal Mass
  64. Normal T4 Ranges in Pregnancy
  65. RAI Treatment While Pregnant
  66. Thyroiditis, or GRTH?
  67. Thyroxin Dose After Thyroidectomy for Papillary Cancer
  68. Iodine Supplements in Hashimoto’s Thyroiditis
  69. Subclinical Hyperthyroidism and Conception
  70. Thyroid Tissue in a Lateral Mass, with Thyroiditis; is It Cancer?
  71. Hyperthyroidism in the Truly Elderly
  72. Thyroxin Absorption Test
  73. Invasive Papillary Cancer and Enlarged Node
  74. Graves Disease and Incidental Thyroid Cancer
  75. Hyperthyroidism and Amenorrhea
  76. Borderline Elevated T3/Subclinical Hyperthyroidism?
  77. Thyroid Hormone Resistance?
  78. Aggressive MTC with Post-op Elevated CT and CEA
  79. Infant with Genetic Problem and Hypothyroidism
  80. A Child with Non-Autoimmune Hyperthyroidism
  81. Hurthle Cell Tumor, Mico-CA, Post-Lobectomy
  82. Cholestasis from MMI
  83. Neonate with Possible Hypothyroidism
  84. Adiation and Breast Feeding
  85. Rai Treatment After Lugol’s Iodine
  86. Thyroid Patient with Asthma, Allergy to Carbimazole, Allery to Ptu?
  87. Preparation for Treatment of a Toxic Adenoma
  88. Possible Resistance to Thyroid Hormone
  89. Minimally Invasive Follicular Carcinoma
  90. Positive I-131 Scan Post Therapeutic I-131
  91. Nodules After RAI Therapy of TMNG
  92. Diagnosis and Treatment of NTIS
  93. Carbimazole Treatment and Hair Loss
  94. Abnormal Thyroid Tests in Pregnancy
  95. Hashimoto’s, Urticaria, and Stomach Pains
  96. Hurthle Cell Carcinoma, Residual Disease Post-op
  97. Chroic Urticaria, Thyroxine Treatment, Thyroid Cancer
  98. Thyroid Hormone Resistance Vs. TSH-oma?
  99. Elevated Hormone Levels, Congenital Hypothyroidism, Psychiatric Problem
  100. Surgery with Adrenal Mass; “Incidental” Medullary Carcinoma
  101. Normal Thyroid Tests Except for Elevated RT3
  102. Congenital Thyroid Deficiency, No Raiu, and Thyroid Cancer
  103. Liver Failure and Severe Thyrotoxicosis
  104. Hypothyroisim, Renal Insufficiency, and RAI Therapy
  105. Thyrotoxicosis and Pregnancy
  106. Thyrotoxic Hypokalemic Paralysis and 131-I Therapy
  107. Thyroid Cyst, and Mild Hyperthyroidism, in Pregnancy
  108. “Subclinical Hypothyroidism” with Normal freeT4 and TSH
  109. Onset Long After
  110. Thyrotoxicosis, Ventricular Fibrillation, Hypokalemia
  111. “Incidental” Medullary Carcinoma
  112. Growing Hot Nodule
  113. Malabsorption of Thyroxine?
  114. Neonate with Large Goiter
  115. Central Hypothyroidism?
  116. Thyroid Hormone and TSH Levels During Pregnancy
  117. Positive Antibodies, and Growing Nodules
  118. Thyroxine Dosage and Surgery, or After 131-I Treatment
  119. 131-I Treatment in Renal Failure
  120. Thyroiditis: Relation to Sertraline, and Lack of Melanin
  121. Atypical Graves’ Disease
  122. Therapy of a Patient with a Solitary Vertebral Metastasis
  123. Amiodarone and Recurrent Graves’ disease
  124. Nodules, Positive Antibodies, and Treatment?
  125. Sublinical Hyperthyroidism and Substernal Goiter
  126. Thyroid Carcinoma Diagnosed by Bronchoscopy
  127. T4 Suppression Therapy Post Radiation Exposure
  128. Follow-up in Differentiated Thyroid Cancers Under 1cm
  129. Hurthle Cell Nodule and Hyperthyroidism in Hashimoto’s Gland
  130. Hives, Angioedema, and Hashimoto’s Thyroiditis
  131. Hyperthyroidism in Pregnancy
  132. Add Recombinant TSH to Endogenous TSH for Ablation?
  133. Hyperthyroidism in Pregnancy; Cause and Treatment?
  134. Amiodarone Induced Thyrotoxicosis
  135. What Condition Does This Person Suffer From?
  136. What to Do with an Incidental 1mm Papillary Cancer?
  137. Therapy of Thyroid Cancer with Known Positive Neck Nodes, Elevated TG, and Negative Scan?
  138. Is This Graves’ Disease?
  139. Hashimoto’s, Transient Hypothyroidism, and an Elevated RAIU
  140. When is a Pentagastrin Test Advised in Following MTC?
  141. How Long to Wait After Operation Before RAI Ablation?
  142. Do We Really Need to Do Both fT4 and TSH in Evaluating Patients?
  143. How to Manage Fetal Hypothyroidism and Goiter
  144. How to Manage Existing Hypothyroidism Perioperatively in a Patient NPO?
  145. How to Treat Sub-clinical Hypothyroidism?
  146. Patient Seeks Counseling About the Possibility of Future Thyroid Exacerbations
  147. “Hashimoto’s Encephalitis”?
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  149. Infant with Chylothorax and Apparent Hypothyroidism
  150. Managing Hashimoto’s in Pregnancy
  151. Does This Person Have Thyroid Hormone Resistance?
  152. Thyroid Hormone Treatment and Uric Acid Level
  153. Thyroxine Requirement During Pregnancy